Results 61 to 70 of about 6,475,800 (310)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

A Hybrid Strategy Two‐Dimensional Concrete Aggregate Filling Algorithm

open access: yesEngineering Reports
Accurate and highly efficient construction of numerical concrete models with different gradations is important to analyze the acoustic properties of ultrasonic waves in concrete. The random aggregates‐based method is a classic approach to meso‐structural
Xu Tian   +4 more
doaj   +1 more source

Enhanced Neural Architecture for Real-Time Deep Learning Wavefront Sensing

open access: yesSensors
To achieve real-time deep learning wavefront sensing (DLWFS) of dynamic random wavefront distortions induced by atmospheric turbulence, this study proposes an enhanced wavefront sensing neural network (WFSNet) based on convolutional neural networks (CNN).
Jianyi Li   +4 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

High-Sensitive Refractive Index Sensing Enabled by Topological Charge Evolution

open access: yesIEEE Photonics Journal, 2020
A high-sensitive refractive index sensor is proposed and demonstrated by utilizing merging bound states in the continuum, namely a set of integer topological charges in the momentum space.
Jiaxin Lv   +5 more
doaj   +1 more source

Design and Analysis of Novel O-Band Low Polarization Sensitive SOA Co-Integrated With Passive Waveguides for Optical Systems

open access: yesIEEE Photonics Journal, 2022
Low polarization-dependent semiconductor optical amplifiers (SOAs) with an easy fabrication process and the capability to be co-integrated with passive elements are crucial in photonic integrated circuits.
Aref Rasoulzadeh Zali   +2 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

An Error Protection Protocol for user-transparent bridging of Fast Ethernet data transmission over the optical fading channel in an Aeronautical environment [PDF]

open access: yes, 2008
This paper presents an extensive insight into error protection techniques for free space optical links, focusing in particular in aeronautic stratospherically applications.
Serrano-Solsona, Clara   +2 more
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