Results 61 to 70 of about 661,766 (323)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Demonstration of analyzers for multimode photonic time-bin qubits

, 2018
We demonstrate two approaches for unbalanced interferometers as time-bin qubit analyzers for quantum communication, robust against mode distortions and polarization effects as expected from free-space quantum communication systems including wavefront ...
Agne, Sascha, Bourgoin, Jean-Philippe, Jennewein, Thomas, Jin, Jeongwan, Lütkenhaus, Norbert, Zhang, Yanbao   +5 more
core   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Structured Optical Receivers for Efficient Deep-Space Communication

, 2017
We discuss conceptual designs for structured optical receivers that can alleviate the requirement for high peak-to-average power ratio in photon-starved optical communication.
Banaszek, Konrad, Jachura, Michał
core   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Long-Range Distributed Vibration Sensing Based on Phase Extraction From Phase-Sensitive OTDR

IEEE Photonics Journal, 2016
Distributed fiber-optic vibration sensors based on phase-sensitive optical time-domain reflectometry ( $\phi$-OTDR) have found many applications in various fields.
Guangyao Yang, Xinyu Fan, Shuai Wang, Bin Wang, Qingwen Liu, Zuyuan He   +5 more
doaj   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Topological protection of continuous frequency entangled biphoton states

Nanophotonics, 2021
Topological quantum optics that manipulates the topological protection of quantum states has attracted special interests in recent years. Here we demonstrate valley photonic crystals implementing topologically protected transport of the continuous ...
Jiang Zhen, Ding Yizhou, Xi Chaoxiang, He Guangqiang, Jiang Chun   +4 more
doaj   +1 more source

High-speed Underwater Wireless Optical Communication: Potential, Challenges, and Possible Solutions [PDF]

, 2017
Traditional underwater communication systems rely on acoustic modems due their reliability and long range. However their limited data rates, lead to the exploration of alternative techniques.
Alouini, Mohamed-Slim
core