Results 111 to 120 of about 3,745,295 (251)

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Optical next generation reservoir computing with complex media

We propose and experimentally demonstrate an optical implementation of the “next generation reservoir computing” (NGRC) algorithm, utilizing large-scale computations via light scattering through complex media.
Hu, Jianqi, Tsuchiyama, Kohei, Gigan, Sylvain, Baek, Yoon Seok, Joly, Malo, Liu, Qiang, Wang, Hao   +6 more
core   +1 more source

Is Computing with Light All You Need? A Perspective on Codesign for Optical Artificial Intelligence and Scientific Computing

Advanced Intelligent Systems
Anything and everything can be solved with light—but under what contexts should one use optical computing and how should optical systems be designed for these tasks?
Prasad P. Iyer, Gaurang R. Bhatt, Saaketh Desai, Elliot J. Fuller, Corinne M. Teeter, François Léonard, Craig M. Vineyard   +6 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Frequency stability of a self-phase-locked degenerate continuous-wave optical parametric oscillator [PDF]

, 2003
The properties of a self-phase-locked by-2-divider optical parametric oscillator are presented. A locking range of up to 156 MHz is measured, and the divider's relative frequency stability is shown to be better than 6/spl times/10/sup -14/
Boller, Klaus J., Lee, D.H., Klein, M.E., Optical Society of America, OSA, Gross, P.   +4 more
core   +1 more source

Optical neural networks: progress and challenges

Light: Science & Applications
Artificial intelligence has prevailed in all trades and professions due to the assistance of big data resources, advanced algorithms, and high-performance electronic hardware.
Tingzhao Fu, Jianfa Zhang, Run Sun, Yuyao Huang, Wei Xu, Sigang Yang, Zhihong Zhu, Hongwei Chen   +7 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Optical Computational Geometry

, 1993
The thesis is devoted to developing optical algorithms for solving problems in computational geometry. An optical model of computation is proposed, in which most classical problems of computational geometry can be solved in O(1) time.
openaire   +2 more sources

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source