Results 131 to 140 of about 179,886 (315)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Exploiting multimode waveguides for pure fibre-based imaging

, 2012
We acknowledge support from the UK Engineering and Physical Science Research CouncilThere has been an immense drive in modern microscopy towards miniaturisation and fibre based technology.
Tomáš Čižmár, Cizmar, Tomas, Dholakia, Kishan, Kishan Dholakia   +3 more
core   +1 more source

High-Speed Microprocessor-Based Optical Instrumentation for the Detection and Analysis of Hydrodynamic Cavitation Downstream of an Additively Manufactured Nozzle

Fluids
This study presents the development and validation of a high-speed optical data acquisition system for detecting and characterizing hydrodynamic cavitation downstream of a triangular nozzle.
Luís Gustavo Macêdo West, André Jackson Ramos Simões, Leandro do Rozário Teixeira, Lucas Ramalho Oliveira, Juliane Grasiela de Carvalho Gomes, Igor Silva Moreira dos Anjos, Antonio Samuel Bacelar de Freitas Devesa, Leonardo Rafael Teixeira Cotrim Gomes, Lucas Gomes Pereira, Iran Eduardo Lima Neto, Júlio Cesar de Souza Inácio Gonçalves, Luiz Carlos Simões Soares Junior, Germano Pinto Guedes, Geydison Gonzaga Demetino, Marcus Vinícius Santos da Silva, Vitor Leão Filardi, Vitor Pinheiro Ferreira, André Luiz Andrade Simões, Luciano Matos Queiroz, Iuri Muniz Pepe   +19 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Narrowband optical heterodyne detection [PDF]

IEEE Journal of Quantum Electronics, 1967
J, Hanlon, S F, Jacobs
openaire   +2 more sources

Sensing with submarine optical cables

APL Photonics
In this paper, we establish the theoretical framework for understanding the sensing capabilities of megameter-long submarine optical cables. We show the distinct advantage of polarization over phase in detecting sub-hertz environmental processes ...
Antonio Mecozzi
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Low-Coherence Integrated Optical Interferometer for Fibre Optic Sensors

This paper proposes and implements a novel scheme for recording signals from fibre optic sensors based on tandem low-coherence interferometry with an integrated optical reference interferometer.
Kirill Sidorenko, Alexey Gorshkov, Oleg Vyazankin, Andrey Lukyanov, Alexander Goryunov, Daniil Semikov, Petr Volkov, Glafira Lemeshevskaya, Aleksey Nezhdanov, Alexander Bobrov   +9 more
core   +1 more source