Results 21 to 30 of about 68,807 (272)

Correlation Between Keratometric and Refractive Astigmatism in Pseudophakes

open access: yesClinical Ophthalmology, 2021
Shavini Athukorala,1 Neal Kansara,2 Erik Lehman,3 Seth M Pantanelli1 1Department of Ophthalmology, Penn State College of Medicine, Hershey, PA, USA; 2Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA; 3Department of Public Health ...
Athukorala S   +3 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Visible and infrared polarization ratio spectroreflectometer [PDF]

open access: yes, 1980
The instrument assists in determining the refractive index and absorption index, at different spectral frequencies, of a solid sample by illuminating the sample at various angles in incidence and measuring the corresponding reflected intensities at ...
Batten, C. E.
core   +1 more source

A unified accretion-ejection paradigm for Black Hole X-ray Binaries

open access: yes, 2005
We present a new picture for the central regions of Black Hole X-ray Binaries. In our view, these central regions have a multi-flow configuration which consists in (1) an outer standard accretion disc down to a transition radius r_J, (2) an inner ...
Aharonian   +96 more
core   +5 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Motion picture camera for optical pyrometry Patent [PDF]

open access: yes, 1962
Filter arrangement for controlling light intensity in motion picture camera used in optical ...
Strass, H. K.
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Study of the inner dust envelope and stellar photosphere of the AGB star R Doradus using SPHERE/ZIMPOL [PDF]

open access: yes, 2016
We use high-angular-resolution images obtained with SPHERE/ZIMPOL to study the photosphere, the warm molecular layer, and the inner wind of the close-by oxygen-rich AGB star R Doradus.
De Beck, E.   +14 more
core   +7 more sources

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