Results 41 to 50 of about 68,807 (272)

The structure–function relationship between multifocal pupil perimetry and retinal nerve fibre layer in glaucoma

BMC Ophthalmology
Background Multifocal pupillographic objective perimetry (mfPOP) is a novel method for assessing functional change in diseases like glaucoma. Previous research has suggested that, in contrast to the pretectally-mediated melanopsin response of ...
Corinne F. Carle, Allan Y. H. Chain, Maria Kolic, Ted Maddess   +3 more
doaj   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Dead Zones around Young Stellar Objects: FU Orionis Outbursts and Transition Discs

, 2012
We perform global time-dependent simulations of an accretion disc around a young stellar object with a dead zone (a region where the magneto-rotational instability cannot drive turbulence because the material is not sufficiently ionised).
Livio, Mario, Lubow, Stephen H., Martin, Rebecca G., Pringle, J. E.   +3 more
core   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Gamma-ray Novae: Rare or Nearby?

, 2016
Classical Novae were revealed as a surprise source of gamma-rays in Fermi LAT observations. During the first 8 years since the LAT was launched, 6 novae in total have been detected to > 5 sigma in gamma-rays, in contrast to the 69 discovered optically in
Brown, Anthony M., Chadwick, Paula M., Cotter, Garret, Morris, Paul J.   +3 more
core   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Cooling Technology for the Optical Disc Drive using Air-flow induced by Disc Rotation

Journal of the Visualization Society of Japan, 2006
Recently, data transfer rates of optical disc drives have been dramatically increasing. To obtain the high data transfer rates, disc rotation speed and laser power also need to be increased. Therefore, to develop the next generation optical disc drives effectively, enhanced cooling system of the optical pick-up unit which includes the laser diode is ...
Takayuki FUJIMOTO, Nobuyuki ISOSHIMA, Hiroyuki TOYODA, Yoshiaki YAMAUCHI, Hitoshi MATSUSHIMA, Ikuo NISHIDA   +5 more
openaire   +2 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Enhanced Track Jump Stability in Optical Disc Drives

Journal of Institute of Control, Robotics and Systems, 2009
Track jump control is a random access strategy for short distance movement. The most common track jump scheme is a bang-bang control of a kick and brake manner. In a conventional track jump scheme, a track-following compensator is turned off during kick and brake periods, and restarted at a target track for track pull-in.
openaire   +2 more sources

Characterization of a circular optical nanoantenna by nonlinear photoemission electron microscopy

, 2015
We report on the investigation of an advanced circular plasmonic nanoantenna under ultrafast excitation using nonlinear photoemission electron microscopy (PEEM) under near-normal incidence.
Falkner, Matthias, Kaiser, Thomas, Klein, Angela, Menzel, Christoph, Pertsch, Thomas, Qi, Jing, Rockstuhl, Carsten, Steinert, Michael   +7 more
core   +1 more source