Results 51 to 60 of about 188,860 (267)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Plasmon-enhanced optical sensors: a review [PDF]

open access: yesThe Analyst, 2015
This paper presents a critical review of recent research progress in plasmonic sensors, plasmon-enhanced fluorescence sensors, and surface-enhanced Raman scattering sensors. It places emphasis on the sensor design strategies, and highlights the applications of sensors in healthcare, homeland security, food safety and environmental monitoring.
Ming, Li   +2 more
openaire   +2 more sources

Resolution enhancement methods in optical microscopy for dimensional optical metrology

open access: yesJournal of the European Optical Society-Rapid Publications
In this paper, we discuss several enhancement approaches to increase the resolution and sensitivity of optical microscopy as a tool for dimensional nanometrology.
Nouri Mohammad   +14 more
doaj   +1 more source

Measurements of the linewidth enhancement factor of mid-infrared quantum cascade lasers by different optical feedback techniques

open access: yesAIP Advances, 2016
Precise knowledge of the linewidth enhancement factor of a semiconductor laser under actual operating conditions is of prime importance since this parameter dictates various phenomena such as linewidth broadening or optical nonlinearities enhancement ...
L. Jumpertz   +6 more
doaj   +1 more source

A Scale-Adaptive Matching Algorithm for Underwater Acoustic and Optical Images

open access: yesSensors, 2020
Underwater acoustic and optical data fusion has been developed in recent decades. Matching of underwater acoustic and optical images is a fundamental and critical problem in underwater exploration because it usually acts as the key step in many ...
Jun Liu   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Electrically regulating nonlinear optical limiting of metal-organic framework film

open access: yesNature Communications, 2022
Nonlinear optical properties of metal-organic framework can be tuned for potential optical applications. Here the authors demonstrate an enhancement the nonlinear absorption coefficient of MOF film by applying external electric field.
Zhi-Zhou Ma   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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