Results 61 to 70 of about 11,595,150 (357)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Observations of artificial and natural optical emissions at the HAARP facility [PDF]

, 2008
Extensive optical observations have been carried out at the High Frequency Active Auroral Research Program (HAARP) ionospheric heating facility since it began operations in 1999.
T. Pedersen, Kendall, E., Esposito, R., Marshall, R., Kosch, M., Pedersen, T., R. Esposito, Mishin, E., R. Marshall, D. Sentman, E. Kendall, M. Kosch, Sentman, D., E. Mishin   +13 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Two-photon-induced photoconductivity enhancement in semiconductor microcavities: a theoretical investigation [PDF]

, 2002
We describe a detailed theoretical investigation of two-photon absorption photoconductivity in semiconductor microcavities. We show that high enhancement (by a factor of >10, 000) of the nonlinear response can be obtained as a result of the microcavity ...
Folliot, H., Krug, T., Barry, Liam P., Dunbar, L.A., Hegarty, J., Lynch, Michael, Donegan, John Francis, Bradley, Ann Louise   +7 more
core  

Giant enhancement of third harmonic generation in an array of graphene ribbons using amplification of surface plasmon polaritons by optical gain

Scientific Reports
In this paper, we theoretically study the enhancement of third-harmonic generation in a plasmonic structure composed of an array of trilayer graphene ribbons sandwiched between two $$CaF_{2}$$ C a F 2 layers.
Marzieh Sedaghat Nejad, Abbas Ghasempour Ardakani   +1 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Optical Properties of Bowtie-Type Nanoantennas Integrated Onto a Silicon Waveguide Platform

IEEE Photonics Journal, 2019
In this paper, we provide a detailed three-dimensional numerical analysis of the optical properties of common and modified bowtie aperture antennas integrated onto a silicon waveguide platform, to discuss the influence of geometrical parameters on the ...
Ye-Fei Dong, Yevhenii M. Morozov, Zichun Le, Anatoliy S. Lapchuk, Song-Long Yao   +4 more
doaj   +1 more source

Use of a DNN-Based Image Translator with Edge Enhancement Technique to Estimate Correspondence between SAR and Optical Images

Applied Sciences, 2022
In this paper, the local correspondence between synthetic aperture radar (SAR) images and optical images is proposed using an image feature-based keypoint-matching algorithm.
Hisatoshi Toriya, Ashraf Dewan, Hajime Ikeda, Narihiro Owada, Mahdi Saadat, Fumiaki Inagaki, Youhei Kawamura, Itaru Kitahara   +7 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

80-Gb/s OTDM system analysis of a vertical microcavity-based saturable absorber for the enhancement of pulse pedestal suppression [PDF]

, 2007
In future high-speed optical time-division-multiplexed (OTDM) systems, an important factor that needs to be considered for optical pulse generation schemes is the impact of pulse pedestals on the overall system performance.
Anandarajah, Prince M., Simon, J.-C., Clarke, A.M., Oudar, Jean-Louis, Anandarajah, P.M., Massoubre, D., Anandarajah, Prince, M., Simon, Jean Claude, Bramerie, L., Maher, R., Guignard, Celine, Barry, Liam P., Bramerie, Laurent, Massoubre, David, Clarke, Aisling M., Simon, Jean-Claude, Barry, L.P., Shen, A., Oudar, J.L., Clarke, Aisling, M., Guignard, C., Barry, Liam, P., Maher, Robert D., Shen, Alexandre   +23 more
core   +1 more source