Results 51 to 60 of about 3,322,116 (291)

The Complex Way to Laser Diode Spectra: Example of an External Cavity Laser With Strong Optical Feedback [PDF]

open access: yes, 2005
An external cavity laser with strong grating-filtered feedback to an antireflection-coated facet is studied with a time-domain integral equation for the electric field, which reproduces the modes of the oscillation condition as steady-state solutions ...
B. TROMBORG   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Performance optimization of free-space optical communication protocols based on results from FSO demonstrations [PDF]

open access: yes, 2007
The mobile free-space optical channel mainly suffers from relatively long link outages, produced by short-term blockings of the line-of-sight (obstacles, clouds), pointing- and tracking-errors or deep signal-fades caused by index of refraction turbulence
Bernhard Epple, Epple, Bernhard
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Optical receiver with optical feedback

open access: yesElectronics Letters, 1987
A new optical receiver with optical feedback is described. The optical feedback is implemented by feeding back a fraction of the light from an optical source which is connected to the output of the receiver, to an extra photodiode. The proposed theoretical model was found to be in good agreement with measurement results on a 5 MHz optical receiver.
openaire   +1 more source

Laser optical feedback imaging controlled by an electronic feedback loop [PDF]

open access: yesJournal of the Optical Society of America A, 2013
In autodyne interferometry, the beating between the reference beam and the signal beam takes place inside the laser cavity and therefore the laser fulfills simultaneously the roles of emitter and detector of photons. In these conditions, the laser relaxation oscillations play a leading role, both in the laser quantum noise, which determines the signal ...
Guillemé, Pierre   +5 more
openaire   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

SELF-MIXING LASER VIBROMETER WITH RESOLUTION IN THE MICRO AND NANO METERS SCALE

open access: yesAnales (Asociación Física Argentina), 2021
We present the development of an interferometer capable of making contactless measurements of vibrations. The results show the we achieve micro- and/or nano-metric measurements without the stabilization of the laser.
L. E. Filgueira, C. T. Schmiegelow
doaj   +1 more source

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