Results 131 to 140 of about 2,210,115 (287)

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani, Laiyi Chua, Wendy J. Komocsar, Amy Larkin, Jordan Johns, Xin Zhang   +5 more
wiley   +1 more source

An Exploration of the Relationships Between Science Identity and Disabled Identities in Undergraduate Science Students

Science Education, EarlyView.
ABSTRACT Science identity is often conceptualized through constructs such as performance, competence, recognition, and interest, with prior research highlighting the roles of race, gender, and cultural background in shaping students' experiences. However, limited scholarship has examined how disability interacts with science identity in postsecondary ...
Ariel Chasen, Maura Borrego
wiley   +1 more source

AT2022sxl: A Candidate Repeating Tidal Disruption Event in Possible Association with Two High-energy Neutrino Events

The Astrophysical Journal
We report a candidate repeating tidal disruption event (TDE), AT2022sxl, found from large-field optical survey data. Two flares with a separation time of ∼7.2 yr between the two optical peaks are observed.
Shunhao Ji, Zhongxiang Wang, Litao Zhu, Stefan Geier, Alok C. Gupta   +4 more
doaj   +1 more source

Fabrication and tolerance reduction of a Si-based pickup module for optical storage

, 2011
We develop a miniaturized optical signal pickup module, with a working wavelength of 650 nm, and an image numerical aperture (NA) of 0.6, comprised of several SiNX optical phase elements on stacked Si substrates, for use in optical storage systems.
Lee, Chien-chien; Wang, Chin-ming; Huang, S.K.; Chang, J. Y.;Chi, Gou-chung; Hsu, S. C.; Liu, C. Y.
core   +1 more source

World Models for Robotic Manipulation: A Survey

SmartBot, EarlyView.
World models enable robots to anticipate how candidate actions may alter object configurations, contact states, and scene geometry before physical execution. This survey examines world models for robotic manipulation as action‐conditioned predictive systems and organizes the literature according to predicted representations, interfaces between ...
Fangyuan Wang, Ziyuan Wang, Guorui Pei, Mengshi Zhang, Canxi Liang, Jun Hu, Zhongxuan Li, Jinsong Wu, Ning Han, Zeqing Zhang, Jiaming Qi, Hongmin Wu, Shiyao Zhang, Pai Zheng, Jia Pan, David Navarro‐Alarcon, Sichao Liu, Peng Zhou   +17 more
wiley   +1 more source

Tracing the Light: Identification for the Optical Counterpart Candidates of Binary Black Holes during O3

The Astrophysical Journal
The accretion disks of active galactic nuclei (AGN) are widely considered the ideal environments for binary black hole mergers and the only plausible sites for their electromagnetic counterparts. M. J. Graham et al.
Lei He, Zhengyan Liu, Rui Niu, Bingzhou Gao, Mingshen Zhou, Purun Zou, Runduo Liang, Wen Zhao, Ning Jiang, Zhen-Yi Cai, Zi-Gao Dai, Ye-Fei Yuan   +11 more
doaj   +1 more source

Driving Drugs Deeper: Force‐Driven Microneedle Systems for Active Therapy and Their Road Towards Clinical Implementation

Small, EarlyView.
Force‐driven microneedles are presented as active therapeutic microdevices that overcome the diffusion limits of conventional patches. By integrating gas generation, magnetic actuation, cavitation, or iontophoresis, these systems drive payloads deeper into tissue, enabling faster, more controlled delivery and highlighting key design principles and ...
Majed Amini, Phoebe Li, Hamed Shahsavan, Mahla Poudineh   +3 more
wiley   +1 more source

Scalable Room‐Temperature Terahertz Graphene Cameras

Small Methods, EarlyView.
ABSTRACT Terahertz (THz) imaging has emerged as a powerful tool for non‐destructive, label‐free analysis across several scientific disciplines, ranging from materials science to biomedical research. By capturing the spatial‐dependent information in a broad range of frequencies, this technique enables the identification of chemical composition ...
Lili Shi, Leonardo Viti, Miriam S. Vitiello   +2 more
wiley   +1 more source

Repeating flares, X-ray outbursts and delayed infrared emission: A comprehensive compilation of optical tidal disruption events

Astronomy & Astrophysics
Tidal disruption events (TDEs) have been proposed as valuable laboratories for studying dormant black holes. However, progress in this field has been hampered by the limited number of observed events.
Langis D. A., Liodakis I., Koljonen K. I. I., Paggi A., Globus N., Wyrzykowski L., Mikołajczyk P. J., Kotysz K., Zieliński P., Ihanec N., Ding J., Morshed D., Torres Z.   +12 more
doaj   +1 more source

Sequential Reduction of Chromite Pellets Using Hydrogen and Silicon Carbide for Carbon Emission Abatement During Ferrochrome Production

steel research international, EarlyView.
H2 prereduction selectively metallizes Fe in UG2 chromite pellets at 1100°C, while silicon carbide becomes active at 1300°C to convert remaining Cr2O3 to carbides and promote Cr metallization. By separating the roles of H2 and SiC, the sequential route reaches up to 65.7% Cr metallization and suppresses in‐furnace CO generation by ≈75% versus ...
D. Coertzen, M. Tangstad, J. P. Beukes, P. G. van Zyl, D. G. Bessarabov, S. P. du Preez   +5 more
wiley   +1 more source