Results 61 to 70 of about 500,433 (311)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Adaptive Fractional-Order Multi-Scale Optimization TV-L1 Optical Flow Algorithm

Fractal and Fractional
We propose an adaptive fractional multi-scale optimization optical flow algorithm, which for the first time improves the over-smoothing of optical flow estimation under the total variation model from the perspective of global feature and local texture ...
Qi Yang, Yilu Wang, Lu Liu, Xiaomeng Zhang   +3 more
doaj   +1 more source

Mutual modality learning for video action classification

Компьютерная оптика, 2023
The construction of models for video action classification progresses rapidly. However, the performance of those models can still be easily improved by ensembling with the same models trained on different modalities (e.g. Optical flow). Unfortunately, it
S.A. Komkov, M.D. Dzabraev, A.A. Petiushko   +2 more
doaj   +1 more source

Attacking Optical Flow

2019 IEEE/CVF International Conference on Computer Vision (ICCV), 2019
ICCV ...
Ranjan, A., Janai, J., Geiger, A., Black, M.   +3 more
openaire   +3 more sources

Decomposition of optical flow on the sphere [PDF]

GEM - International Journal on Geomathematics, 2014
The final publication is available at link.springer ...
Kirisits, Clemens, Lang, Lukas F., Scherzer, Otmar   +2 more
openaire   +3 more sources

A Robust and Discontinuity-Preserving Approach to Optical Flow Estimation

, 2009
In this paper we develop a robust and discontinuity-preserving approach based on local and global combined model for the optical flow estimation. Firstly, the local and global optical flow methods are combined to yield dense flow fields that are robust ...
Chen FL(陈法领), Haibo Luo, Faling Chen, Luo HB(罗海波)   +3 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Adaptive Remote Sensing Paradigm for Real-Time Alerting of Convulsive Epileptic Seizures

Sensors, 2023
Epilepsy is a debilitating neurological condition characterized by intermittent paroxysmal states called fits or seizures. Especially, the major motor seizures of a convulsive nature, such as tonic–clonic seizures, can cause aggravating consequences ...
Stiliyan Kalitzin
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source