Results 71 to 80 of about 445,901 (262)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

On discontinuous optical flow

Comput. Artif. Intell., 2000
This paper deals with an analysis of image motion in frequency space with respect to motion discontinuities and surface translucence. The frequency structure of motion discontinuities due to occlusion is derived under models of constant and linear optical flow. Authors demonstrate its various geometrical properties.
Beauchemin, S. S., Barron, J. L.
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Real‐time running detection system for UAV imagery based on optical flow and deep convolutional networks

IET Intelligent Transport Systems, 2020
A fast‐running human detection system for the unmanned aerial vehicle (UAV) based on optical flow and deep convolution networks is proposed in this study.
Qingtian Wu, Yimin Zhou, Xinyu Wu, Guoyuan Liang, Yongsheng Ou, Tianfu Sun   +5 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

High-Speed Robust Dynamic Positioning and Tracking Method Based on Visual Visible Light Communication Using Optical Flow Detection and Bayesian Forecast

IEEE Photonics Journal, 2018
There are three critical elements in visible light positioning (VLP) system: Positioning accuracy, real-time ability, and robustness. However, most of the existing VLP studies only focus on the positioning accuracy and only a few studies consider the ...
Weipeng Guan, Xin Chen, Mouxiao Huang, Zixuan Liu, Yuxiang Wu, Yingcong Chen   +5 more
doaj   +1 more source

Amodal Optical Flow

2024 IEEE International Conference on Robotics and Automation (ICRA)
Optical flow estimation is very challenging in situations with transparent or occluded objects. In this work, we address these challenges at the task level by introducing Amodal Optical Flow, which integrates optical flow with amodal perception. Instead of only representing the visible regions, we define amodal optical flow as a multi-layered pixel ...
Luz, Maximilian, Mohan, Rohit, Sekkat, Ahmed Rida, Sawade, Oliver, Matthes, Elmar, Brox, Thomas, Valada, Abhinav   +6 more
openaire   +3 more sources