Results 41 to 50 of about 8,813,709 (334)

In vivo optical imaging of physiological responses to photostimulation in human photoreceptors [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2016
Significance Using a full-field optical coherence tomography system, we measured changes in the time that light requires to pass through photoreceptor outer segments, when the retina is stimulated by a light pulse.
Dierck Hillmann, H. Spahr, C. Pfäffle, H. Sudkamp, G. Franke, G. Hüttmann   +5 more
semanticscholar   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Targeted Optical Imaging Agents in Cancer: Focus on Clinical Applications

Contrast Media & Molecular Imaging, 2018
Molecular imaging is an emerging strategy for in vivo visualization of cancer over time based on biological mechanisms of disease activity. Optical imaging methods offer a number of advantages for real-time cancer detection, particularly in the ...
B. Joshi, Thomas D. Wang
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Probing delivery of a lipid nanoparticle encapsulated self-amplifying mRNA vaccine using coherent Raman microscopy and multiphoton imaging

Scientific Reports
The COVID-19 pandemic triggered the resurgence of synthetic RNA vaccine platforms allowing rapid, scalable, low-cost manufacturing, and safe administration of therapeutic vaccines.
Kajari Bera, Renán A. Rojas-Gómez, Prabuddha Mukherjee, Corey E. Snyder, Edita Aksamitiene, Aneesh Alex, Darold R. Spillman, Marina Marjanovic, Ahmed Shabana, Russell Johnson, Steve R. Hood, Stephen A. Boppart   +11 more
doaj   +1 more source

Deep Learning-Based 3D Measurements with Near-Infrared Fringe Projection

Sensors, 2022
Fringe projection profilometry (FPP) is widely applied to 3D measurements, owing to its advantages of high accuracy, non-contact, and full-field scanning.
Jinglei Wang, Yixuan Li, Yifan Ji, Jiaming Qian, Yuxuan Che, Chao Zuo, Qian Chen, Shijie Feng   +7 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Accelerating biopharmaceutical cell line selection with label-free multimodal nonlinear optical microscopy and machine learning

Communications Biology
The selection of high-performing cell lines is crucial for biopharmaceutical production but is often time-consuming and labor-intensive. We investigated label-free multimodal nonlinear optical microscopy for non-perturbative profiling of ...
Jindou Shi, Alexander Ho, Corey E. Snyder, Eric J. Chaney, Janet E. Sorrells, Aneesh Alex, Remben Talaban, Darold R. Spillman, Marina Marjanovic, Minh Doan, Gary Finka, Steve R. Hood, Stephen A. Boppart   +12 more
doaj   +1 more source

Design and Applications of Liquid Crystal Biophotonic Sensors for Ion Detection

Advanced Photonics Research, 2022
Liquid crystals (LCs) are nanophotonic materials which can interact with light in the molecular scale. While the LCs are widely used in various displays, last decade has witnessed emerging applications of the LCs for nondisplays.
Ruixiang Qu, Guoqiang Li
doaj   +1 more source

Analysis of Polarization Detector Performance Parameters on Polarization 3D Imaging Accuracy

Sensors, 2023
Three-dimensional (3D) reconstruction of objects using the polarization properties of diffuse light on the object surface has become a crucial technique.
Pengzhang Dai, Dong Yao, Tianxiang Ma, Honghai Shen, Weiguo Wang, Qingyu Wang   +5 more
doaj   +1 more source