Results 221 to 230 of about 152,698 (262)

WHOLE GENOME OPTICAL MAPPING [PDF]

open access: possibleProceedings of the 4th Asia-Pacific Bioinformatics Conference, 2005
An innovative new technology, optical mapping, is used to infer the genome map of the location of short sequence patterns called restriction sites. The technology, developed by David Schwartz, allows the visualization of the maps of randomly located single molecules around a million base pairs in length.
openaire   +1 more source

Potential mapping of optical tweezers

Optics Letters, 2011
Optical tweezers are very often used for measurement of piconewton range forces. Depending on the displacement of the trapped bead, the trap may become stiffer which causes considerable underestimation of the measured force. We have shown, both by theory and experiment, that such a stiffening occurs for beads larger than 0.5 μm in radius. For the first
Tahmineh, Godazgar   +2 more
openaire   +2 more sources

Intensity mapping optical aberrations

Applied Optics, 1978
Intensity mapping aberrations for high average power laser beams are examined from the point of view of diffraction theory. For the Fresnel ripple aberrations, it was determined that indeed they behave like a circular diffraction grating where energy is diffracted into the far wings of the far-field intensity distribution without significantly ...
P V, Avizonis, B D, O'Neil, V A, Hedin
openaire   +2 more sources

A Quantile Method for Sizing Optical Maps

Journal of Computational Biology, 2007
Optical mapping is an integrated system for the analysis of single DNA molecules. It constructs restriction maps (noted as "optical map" ) from individual DNA molecules presented on surfaces after they are imaged by fluorescence microscopy. Because restriction digestion and fluorochrome staining are performed after molecules are mounted, resulting ...
Haifeng Li   +4 more
openaire   +2 more sources

Coherent Optics in Mapping

Optical Engineering, 1975
Several potential applications of coherent optics in the field of topographic mapping have been identified.1 This paper outlines the motivation for applying coherent optics to topographic mapping, presents some additional applications not included in Ref. 1, and further discusses some applications developed in that reference.
N. Balasubramanian, R. D. Leighty
openaire   +1 more source

History of Optical Mapping

2021
Optical mapping is an imaging technique that is used to record physiologic phenomena from live tissue. To date, optical imaging has been applied in the heart to record NADH+, transmembrane potential, and intracellular calcium transients. While NADH+ imaging relies on the intrinsic fluorescent signals from the tissue, fluorescent dyes have been ...
openaire   +1 more source

Genomics via Optical Mapping II: Ordered Restriction Maps

Journal of Computational Biology, 1997
In this paper, we describe our algorithmic approach to constructing ordered restriction maps based on the data created from the images of population of individual DNA molecules (clones) digested by restriction enzymes. The goal is to devise map-making algorithms capable of producing high-resolution, high-accuracy maps rapidly and in a scalable manner ...
Thomas S. Anantharaman   +2 more
openaire   +2 more sources

Optical Mapping of Arrhythmias

2000
Optical mapping of voltage dependent fluorescence in cardiac tissue allows for the simultaneous measurement of membrane potential from many locations on the surface of the heart. The development of this technology has revolutionized the field of cardiac electrophysiology and has provided new insights into the mechanisms of initiation and maintenance of
Gregory E. Morley   +2 more
openaire   +1 more source

Optical Mapping Applications

SPIE Proceedings, 1988
Holography can be used for arbitrary, parallel, weighted mappings between planes with up to to 106 pixels each at I/O limited rates. This allows precalculated mappings to occur at very high speed. The applicarttions for one-to-one, one-to-many, many-to-one, and many-to-many maps are explored here.
openaire   +1 more source

Optical map transformations

Optics Communications, 1974
Abstract An optical technique for performing general types of map transformations is introduced. Using a coherent system, the object distribution is multiplied by a phase function so that its frequency spectrum constitutes the transformation wanted. Also shown is how imaging systems can be made space variant.
openaire   +1 more source

Home - About - Disclaimer - Privacy