Results 91 to 100 of about 1,684,231 (305)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Grating Bio-Microelectromechanical Platform Architecture for Multiple Biomarker Detection
BiosensorsA label-free biosensor based on a tunable MEMS metamaterial structure is proposed in this paper. The adopted structure is a one-dimensional array of metamaterial gratings with movable and fixed fingers.
Fahimeh Marvi +2 more
doaj +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Optical issues in measuring strabismus
Middle East African Journal of Ophthalmology, 2015 Potential errors and complications during examination and treatment of strabismic patients can be reduced by recognition of certain optical issues. This articles reviews basic as well as guiding principles of prism optics and optics of the eye to equip the reader with the necessary know-how to avoid pitfalls that are commonly encountered when using ...
openaire +3 more sources
High speed optical tomography for flow visualization [PDF]
A novel optical architecture (based on holographic optical elements) for making high speed tomographic measurements is presented. The system is designed for making density or species concentration measurements in a nonsteady fluid or combustion flow ...
Hesselink, Lambertus, Snyder, Ray
core +1 more source
Photon Antibunching and Magnetospectroscopy of a Single Fluorine Donor in ZnSe
, 2010 We report on the optical investigation of single electron spins bound to fluorine donor impurities in ZnSe. Measurements of photon antibunching establish the presence of single, isolated optical emitters, and magneto-optical studies are consistent with ...
Clark, S. M. +8 more
core +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
SensorsWe describe a method for reducing the cost of optical frequency domain reflectometer (OFDR) hardware by replacing two reference channels, including an auxiliary interferometer and a gas cell, with a single channel.
Maxim E. Belokrylov +4 more
doaj +1 more source
Rigid Body Motion Estimation based on the Lagrange-d'Alembert Principle
, 2015 Stable estimation of rigid body pose and velocities from noisy measurements, without any knowledge of the dynamics model, is treated using the Lagrange-d'Alembert principle from variational mechanics.
Barany, Ernest +3 more
core +1 more source