Results 121 to 130 of about 700,724 (318)

Sagnac interferometry for high-sensitivity optical measurements of spin-orbit torque. [PDF]

Sci Adv, 2023
Karimeddiny S, Cham TMJ, Smedley O, Ralph DC, Luo YK.   +4 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

A high-speed optical star network using TDMA and all-optical demultiplexing techniques [PDF]

, 1996
The authors demonstrate the use of time-division multiplexing (TDM) to realize a high capacity optical star network. The fundamental element of the demonstration network is a 10 ps, wavelength tunable, low jitter, pulse source. Electrical data is encoded
Remi Boittin, Barry, Liam P., Guignard, Celine, Jean Debeau, Debeau, J., Liam P. Barry, Boittin, R., Bernard, M., Martine Bernard   +8 more
core   +1 more source

Non-destructive optical measurement of transparent objects: a review

Light: Advanced Manufacturing
Transparent objects are widely used in various fields, leading to increasing demand for methods of measuring them. However, the measurement of such objects has always been challenging owing to the intricate refraction and reflection phenomena they ...
Hongda Quan, Wenqi Shi, Lingbao Kong
doaj   +1 more source

Optically measuring barcodes [PDF]

Nature Methods, 2020
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Slow-light and evanescent modes at interfaces in photonic crystal waveguides: optimal extraction from experimental near-field measurements [PDF]

, 2011
We develop a systematic approach for simultaneous extraction of the dispersion relations and profiles of multiple modes in periodic waveguides though a special global optimization procedure applied to near-field electric field measurements in the ...
Ha, S., de Sterke, C. Martijn, Yuri S. Kivshar, Krauss, T.F., Sterke, C.M. de, Spasenovic, Marko, White, Tom P, Sukhorukov, Andrey A., Krauss, Thomas Fraser, Thomas F. Krauss, White, T.P., Sangwoo Ha, Kuipers, L.K. (Kobus), Sukhorukov, A.A., Kivshar, Y.S. (Yuri), Thomas P. White, Andrey A. Sukhorukov, Kuipers, L. Kobus, L. (Kobus) Kuipers, Spasenović, M., Marko Spasenović, C. Martijn de Sterke, Ha, Sangwoo, Kivshar, Yuri S.   +23 more
core   +1 more source

Protein Identification and Quantification Using Porous Silicon Arrays, Optical Measurements, and Machine Learning. [PDF]

Biosensors (Basel), 2023
Ward SJ, Cao T, Zhou X, Chang C, Weiss SM.   +4 more
europepmc   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Performance of a photothermal detector with turbid liquids [PDF]

, 2005
A closed-cell photothermal detector for aqueous analytes has been evaluated at 254nm and 678nm. The detector used a water meniscus as a pressure sensor, whose periodic deflection was measured using a low finesse optical fibre Fabry-Perot interferometer.
Johnson, Mark, Hodgkinson, Jane, Dakin, John P.   +2 more
core   +1 more source