Results 31 to 40 of about 186,050 (217)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Modeling and Analysis of an 80-Gbit/s SiGe HBT Electrooptic Modulator
IEEE Photonics Journal, 2011 We present a rigorous electrical and optical analysis of a strained and graded base SiGe Heterojunction Bipolar Transistor (HBT) electrooptic (EO) modulator.
Tuhin Guha Neogi +7 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Results in PhysicsA comprehensive understanding of the nonlinear optical characteristics of materials is essential for the development of nonlinear optical applications and the advancement of all-optical devices. Nonlinear phase modulation is emerging as an attractive and
Amir Namiq Hassan, Mohammad Ali Haddad
doaj +1 more source
The Journal of Engineering, 2019 A frequency-tunable terahertz (THz) wave generation scheme based on an optically injected semiconductor laser is proposed for radar and communication applications.
Fangzheng Zhang +3 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Photonics, 2022 We demonstrate 60 GHz separation optical two-tone signal generation at arbitrary C-band wavelengths without involving complicated optical wavelength filtering.
Akito Chiba, Yosuke Akamatsu
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
IET Radar, Sonar & Navigation, 2021 Frequency shift keying (FSK) signal has been widely used in modern radar systems. To intercept the FSK radar signal with a high interception probability, radar reconnaissance receiver should have an ultra‐wideband receiving ability.
Zhaoyang Qiu +5 more
doaj +1 more source