Results 101 to 110 of about 123,133 (293)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Ultrafast Modulation of Optical Metamaterials

Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, 2009
We show by pump-probe spectroscopy that the optical response of a fishnet metamaterial can be modulated on the femtosecond time scale. The modulation dynamics is dominated by pump-induced changes in the constituting dielectric medium, but the strength of modulation is dramatically enhanced through the plasmon resonance.
David J, Cho, Wei, Wu, Ekaterina, Ponizovskaya, Pratik, Chaturvedi, Alexander M, Bratkovsky, Shih-Yuan, Wang, Xiang, Zhang, Feng, Wang, Y Ron, Shen   +8 more
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A Parallel Multi-channel Lithium Niobate Electro-optic Modulator

Guangtongxin yanjiu
【Objective】In order to solve the technical problems of large volume, low integration and small bandwidth of electro-optic modulator, a design method of parallel multi-channel thin film Lithium niobate electro-optic modulator is proposed.
YANG Pengyi
doaj  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Sub-Femtojoule Hybrid Plasmonic Optical Modulator

IEEE Photonics Journal, 2019
A highly compact optical modulator is proposed and analyzed. The modulator is based on the hybrid plasmonic waveguide platform. The structure of the modulator is built from silicon, silver, and electro-optical polymer layers.
S. M. Sherif, Mohamed Elsayed, Lamees A. Shahada, Mohamed A. Swillam   +3 more
doaj   +1 more source

Communication system uses modulated laser beam [PDF]

, 1965
Electro-optical system is placed on a satellite to effect communications between two remote stations.
Minott, P. O.
core   +1 more source

Upper Bound Imposed upon Responsivity of Optical Modulators

, 2005
We study theoretically the responsivity of optical modulators. For the case of linear response we find using perturbation theory an upper bound imposed upon the responsivity.
Berry, Buks, Eyal Buks
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

All-optical nonvolatile optical modulator for in-fiber operation. [PDF]

Nanophotonics, 2023
Liu Z, Li X, Cheng S, Li Y, Jin W, Zhang Y, Qin Y, Zhang Y, Li S, Lotnyk A, Yuan L.   +10 more
europepmc   +1 more source