Results 121 to 130 of about 7,039,787 (310)

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou   +16 more
wiley   +1 more source

Investigation of the tolerance of wavelength-routed optical networks to traffic load variations. [PDF]

open access: yes, 2006
This thesis focuses on the performance of circuit-switched wavelength-routed optical network with unpredictable traffic pattern variations. This characteristic of optical networks is termed traffic forecast tolerance.
Lao, Ningning, Lao, N.
core  

Scalable Passive Optical Network Architecture for Reliable Service Delivery

open access: yes, 2011
A scalable and reliable architecture for both a wavelength division multiplexing passive optical network and a hybrid wavelength and time division multiplexing passive optical network with self-healing capability is presented and evaluated.
Chen, Jiajia,   +7 more
core   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Regenerator Placement with Guaranteed Connectivity in Optical Networks

open access: yes, 2007
The problem of minimizing the number of optical nodes with signal regeneration capability can be constrained to guarantee a desired degree of end-to-end connectivity in the all-optical transport network. The problem can be formulated using a k -connected,
Savasini, Marcio S.,   +4 more
core   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

AN OPTICAL PACKAGE FOR A RECONFIGURABLE FREE-SPACE OPTICAL INTERCONNECTION NETWORK FOR MULTIPROCESSOR SYSTEMS

open access: yes, 1995
An optical package for a reconfigurable free-space optical interconnection network based on a novel (2,2,2) switching node for the multiprocessor system is presented.
ZHAO XJ   +7 more
core  

An Error Protection Protocol for user-transparent bridging of Fast Ethernet data transmission over the optical fading channel in an Aeronautical environment [PDF]

open access: yes, 2008
This paper presents an extensive insight into error protection techniques for free space optical links, focusing in particular in aeronautic stratospherically applications.
Serrano-Solsona, Clara   +2 more
core  

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