Results 101 to 110 of about 331,774 (318)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Frequency-Multiplexed Barker-Coded Φ-OTDR for High-Speed Distributed Acoustic Sensing

IEEE Photonics Journal
Pulse pre-coding Φ-OTDR has been widely employed to enhance the signal-to-noise ratio (SNR) of recovery perturbation while with the compromising of interrogation frequency. In this paper, a novel frequency-multiplexed Barker-coded Φ-OTDR is
Wanxin Li, Zhiyang Xue, Zheyuan Lin, Dongdong Zou, Huan Huang, Shanshan Cao, Yi Cai   +6 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Multiple-Hop Routing in Ultrafast All-Optical Packet Switching Network Using Multiple PPM Routing Tables

, 2008
In this paper we present the modeling and simulation of multiple-hop routing in ultrafast all-optical packet switching based routers employing multiple pulse position modulation (PPM) formatted routing table.
Ghassemlooy, Zabih, H. Le Minh, Ng, Wai Pang, M.F. Chiang, Z. Ghassemlooy, Wai Pang Ng, Chiang, Ming-Feng, A.A. El Aziz, Le Minh, Hoa, Abd El Aziz, Ahmad   +9 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Snapshot multispectral imaging using a diffractive optical network. [PDF]

Light Sci Appl, 2023
Mengu D, Tabassum A, Jarrahi M, Ozcan A.
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Modeling optimization design and amplification characteristics of O-band irregular Bragg bismuth-doped fiber amplifier

Results in Physics
In recent years, O-band bismuth-doped fiber amplifier (BDFA) have been rapidly developed due to the fluorescence properties of bismuth-doped glass in the near-infrared (NIR) band, while there are still few studies on bismuth-doped fibers (BDF) with large
Dingchen Wang, Li Pei, Jingjing Zheng, Jianshuai Wang, Wenxuan Xu, Jing Li, Tigang Ning   +6 more
doaj   +1 more source

Time-Series Representation Learning in Topology Prediction for Passive Optical Network of Telecom Operators. [PDF]

Sensors (Basel), 2023
Zhao H, Fang Y, Zhao Y, Tian Z, Zhang W, Feng X, Yu L, Li W, Fan H, Mu T.   +9 more
europepmc   +1 more source