Results 91 to 100 of about 1,807,617 (309)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Optical Performance Monitoring for Intra-LP-Mode Dispersion in Weakly-Coupled Mode-Division Multiplexed Systems

IEEE Photonics Journal, 2022
Weakly-coupled mode-division multiplexing (MDM) technique based on linearly-polarized (LP) modes in ultralow-modal-crosstalk few-mode fiber (FMF) has been considered as a promising candidate for capacity enhancement of next-generation optical ...
Mingqing Zuo, Jiaxin Liu, Gang Qiao, Lei Shen, Yuyang Gao, Dawei Ge, Yongqi He, Zhangyuan Chen, Juhao Li   +8 more
doaj   +1 more source

Real-Time Elderly Monitoring for Senior Safety by Lightweight Human Action Recognition [PDF]

the 16th IEEE International Symposium on Medical Information and Communication Technology (ISMICT), Virtual Conference, May 2 - 4, 2022, 2022
With an increasing number of elders living alone, care-giving from a distance becomes a compelling need, particularly for safety. Real-time monitoring and action recognition are essential to raise an alert timely when abnormal behaviors or unusual activities occur.
arxiv  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

The Firmware Design and Implementation Scheme for C Form-Factor Pluggable Optical Transceiver

Applied Sciences, 2020
The demand for integrated telecommunication network infrastructure has increased, and 100 Gbps optical transceivers are a critical part of this infrastructure.
Jae-Woo Kim, Dong-Seong Kim, Seung-Hwan Kim, Sang-Moon Shin   +3 more
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Machine Learning in Short-Reach Optical Systems: A Comprehensive Survey

Photonics
Recently, extensive research has been conducted to explore the utilization of machine learning (ML) algorithms in various direct-detected and (self)-coherent short-reach communication applications.
Chen Shao, Elias Giacoumidis, Syed Moktacim Billah, Shi Li, Jialei Li, Prashasti Sahu, André Richter, Michael Faerber, Tobias Kaefer   +8 more
doaj   +1 more source

Concept and development of an autonomous wearable micro-fluidic platform for real time pH sweat analysis [PDF]

, 2012
In this work the development of an autonomous, robust and wearable micro-fluidic platform capable of performing on-line analysis of pH in sweat is discussed.
Angelov, Nikolay, Benito-Lopez, Fernando, Byrne, Robert, Coyle, Shirley, Curto, Vincenzo F., Diamond, Dermot   +5 more
core   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

مراقبة تشتت نمط الاستقطاب PMD من خلال قياس مطال النبضات الناتجة عن جمع مركبتي الاستقطاب المتعامدتين

مجلة جامعة دمشق للعلوم الهندسية, 2021
في هذا البحث تم اقتراح تقنية جديدة لمراقبة تشتت نمط الاستقطاب polarization mode dispersion (PMD) في شبكات الألياف الضوئية. تعتمد التقنية على تحويل مركبتي الاستقطاب المتعامدتين للإشارة الضوئية المراقبة إلى نفس حالة الاستقطاب ومن ثم يتم جمعهما معاً بفرق ...
د. حيدرا عبد الرحمن عبد الله
doaj