Results 41 to 50 of about 555,181 (241)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
BiosensorsAccurate malaria diagnosis is essential for effective case management and transmission control; however, the sensitivity, operational requirements, and field applicability of current conventional methods are limited.
Afiat Berbudi +3 more
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
AIP Advances, 2014 Optical eigenstates in a concentrically symmetric resonator are photonic angular momentum states (PAMSs) with quantized optical orbital angular momentums (OAMs). Nonreciprocal optical phenomena can be obtained if we lift the degeneracy of PAMSs.
Tian-Jing Guo +5 more
doaj +1 more source
Nonlinear optical effects in artificial materials
, 2007 We consider some nonlinear phenomena in metamaterials with negative refractive index properties. Our consideration includes a survey of previously known results as well as identification of the phenomena that are important for applications of this new ...
Gabitov, Ildar R., Maimistov, Andrei I.
core +1 more source
Periodic optical variability and debris accretion in white dwarfs: a test for a causal connection [PDF]
, 2018 Recent Kepler photometry has revealed that about half of white dwarfs (WDs) have periodic, low-level (~ 1e-4 - 1e-3), optical variations. Hubble Space Telescope (HST) ultraviolet spectroscopy has shown that up to about one half of WDs are actively ...
Agol, Eric +11 more
core +2 more sources
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Color Masking of Two Types of Medium Translucency Lithium Disilicate Ceramic Restorations by Spectrophotometry [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i BābulBackground and Objective: One of the problems in aesthetic treatment is the fabrication of monolithic ceramic restorations that have both the ability to cover discolored substrate and appropriate translucency so that it can have similar appearance to the
T Rostamzadeh +2 more
doaj