Results 71 to 80 of about 9,925 (314)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Highly Sensitive Optical Receivers

open access: yes, 2006
Highly Sensitive Optical Receivers primarily treats the circuit design of optical receivers with external photodiodes. Continuous-mode and burst-mode receivers are compared.
Zimmermann, Horst, Schneider, Kerstin
core   +1 more source

A High-Speed Fully-Integrated VLC Receiver With Large-Area Photodetector

open access: yesIEEE Photonics Journal
This paper presents a fully integrated visible light communication (VLC) receiver with a large photo-sensitive area optimized for high-speed data transmission. The photodetector (PD) featuring a size of 410 μm × 410 μm is implemented
Sheng Xie, Xiaoxia Hu, Jia Cong
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Bit error performance of diffuse indoor optical wireless channel pulse position modulation system employing artificial neural networks for channel equalisation

open access: yes, 2009
The bit-error rate (BER) performance of a pulse position modulation (PPM) scheme for non-line-of-sight indoor optical links employing channel equalisation based on the artificial neural network (ANN) is reported.
Ghassemlooy, Zabih   +2 more
core   +1 more source

Multi-Antenna GNSS-Over-Fiber Architecture for Extensive Remote Multi-Baseline Network

open access: yesIEEE Photonics Journal, 2020
GNSS carrier-phase-based double-difference positioning has been widely used in various precision positioning systems. This paper proposes a cost-effective scheme for an extensive multi-antenna remote multi-baseline network using a single GNSS-over-fiber ...
Puyu Liu   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Evaluation of Optical Receiver Modes Using a Schrödinger Equation

open access: yesPhotonics
In optical receiver mode (ORM) division multiplexing optical communication systems, which can ultimately achieve a very high spectral efficiency, an accurate evaluation of the ORMs is crucial.
Kyung Hee Seo, Jae Seung Lee
doaj   +1 more source

Introductory survey for wireless infrared communications

open access: yesThe Journal of Engineering, 2014
Wireless infrared communications can be defined as the propagation of light waves in free space using infrared radiation whose range is 400–700 nm.
Munsif Ali Jatoi, Nidal Kamel
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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