Results 81 to 90 of about 3,504,310 (335)

Multi-Antenna GNSS-Over-Fiber Architecture for Extensive Remote Multi-Baseline Network

open access: yesIEEE Photonics Journal, 2020
GNSS carrier-phase-based double-difference positioning has been widely used in various precision positioning systems. This paper proposes a cost-effective scheme for an extensive multi-antenna remote multi-baseline network using a single GNSS-over-fiber ...
Puyu Liu   +5 more
doaj   +1 more source

Electro-optical spin measurement system [PDF]

open access: yes, 1990
An electro-optical spin measurement system for a spin model in a spin tunnel includes a radio controlled receiver/transmitter, targets located on the spin model, optical receivers mounted around the perimeter of the spin tunnel and the base of the spin ...
Fodale, Robert, Hampton, Herbert R.
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Toward Practical Digital Phase Alignment for Coherent Beam Combining in Multi-Aperture Free Space Coherent Optical Receivers

open access: yesIEEE Access, 2020
In free space optical communication systems, multi-aperture coherent optical receivers based on digital coherent beam combining (D-CBC) technique can provide exceptionally high sensitivity and are more robust to the atmosphere turbulence compared with ...
Chenjie Rao   +4 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Novel configuration of finite-impulse-response filters tolerant to carrier-phase fluctuations in digital coherent optical receivers for higher-order quadrature amplitude modulation signals.

open access: yesOptics Express, 2012
We propose a novel configuration of the finite-impulse-response (FIR) filter adapted by the phase-dependent decision-directed least-mean-square (DD-LMS) algorithm in digital coherent optical receivers.
Y. Mori, Chao Zhang, K. Kikuchi
semanticscholar   +1 more source

The Submillimeter Array

open access: yes, 2004
The Submillimeter Array (SMA), a collaborative project of the Smithsonian Astrophysical Observatory (SAO) and the Academia Sinica Institute of Astronomy and Astrophysics (ASIAA), has begun operation on Mauna Kea in Hawaii. A total of eight 6-m telescopes
Blundell R.   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

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