Results 91 to 100 of about 224,858 (315)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A transverse loading technique to enhance the pressure measurement capability of fibre Bragg gratings [PDF]

, 2008
A fibre optic pressure sensor based on the application of a transverse load onto an epoxy-resin material embedded over a sub-section of a fibre Bragg grating (FBG) is presented.
R. Correia, E. Chehura, R. P. Tatam, Tatam, Ralph P., S. W. James, Chehura, Edmon, Correia, Ricardo N., James, Stephen W.   +7 more
core   +1 more source

Underwater optical wireless sensor network for real-time underwater environmental monitoring

, 2022
With the growing number of underwater vehicles and devices used for marine environmental monitoring, there is an urgent need for real-time and high-speed underwater wireless communication technologies to transmit huge amounts of data.
Ng, Tien Khee, Kang, Chun Hong, Ooi, Boon S., Kong, Meiwei, Alkhazragi, Omar, Guo, Yujian, Sait, Mohammed   +6 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Underwater optical wireless sensor network [PDF]

The thesis details the development of a short range, multi-hop underwater optical wireless sensor network. Multi-hop underwater optical wireless communication using a line of sight (LOS) link can provide a greater range compared to a single hop ...
Ahmad, Zahir Uddin
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Resonantly enhanced Faraday rotation in a microcoil current sensor

, 2012
A proof-of-principle experimental demonstration with theoretical modeling is presented for resonantly enhanced Faraday rotation in a microcoil current sensor.
Ismaeel, R., Newson, T.P., Newson, T., Chen, G., Lee, T., Brambilla, G., Chen, G.Y.   +6 more
core   +1 more source

Indium tin oxide overlayered waveguides for sensor applications [PDF]

, 1997
The use of indium tin oxide (ITO) thin films as electrodes for integrated optical electrochemical sensor devices is discussed. The effect of various thicknesses of ITO overlayers exhibiting low resistivity and high transparency on potassium ion-exchanged
Wilkinson, James S., LUFF J. B., Perrone, Guido, Wilkinson, J.S., Luff, B.Jonathan, WILKINSON J. S., Luff, J.B.   +6 more
core   +1 more source

Bio-Chemical Sensors Based on Excessively Tilted Fiber Grating

Photonic Sensors
Excessively tilted fiber gratings (ExTFGs) are a type of special optical fiber grating device different from traditional fiber Bragg gratings, long period fiber gratings, and tilted fiber Bragg gratings.
Fudan Chen, Hong Gu, Binbin Luo, Shenghui Shi   +3 more
doaj   +1 more source