Results 111 to 120 of about 596,265 (301)

Concepts for a cost-efficient, additively manufactured WR90 coaxial waveguide transition [PDF]

Advances in Radio Science
This publication focuses on the production of low-cost prototypes of coaxial-waveguide transitions (CWTs) that achieve the performance level of industrial WR90 and WR187 CWTs.
M. Falk, S. Müller, V. Lücken, A. R. Diewald   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

A Precision Angle Sensor using an Optical Lever inside a Sagnac Interferometer

, 2011
We built an ultra low noise angle sensor by combining a folded optical lever and a Sagnac interferometer. The instrument has a measured noise floor of 1.3 prad / Hz^(1/2) at 2.4 kHz.
A. Sugarbaker, Ando, D. M. S. Johnson, Dixon, Howell, J. Hammer, J. M. Hogan, Lorrain, M. A. Kasevich, Numata, Putman, S. Dickerson, S.-W. Chiow, Starling, T. Kovachy   +14 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A Laser-Induced Breakdown Spectroscopy (LIBS) Instrument for In-Situ Exploration with the DLR Lightweight Rover Unit (LRU)

Applied Sciences
In the framework of the Helmholtz ARCHES project, a multitude of robots, including rovers and drones, were prepared for the autonomous exploration of a test site at the foothills of Mt. Etna, Sicily—a terrain resembling extraterrestrial locations such as
Susanne Schröder, Fabian Seel, Enrico Dietz, Sven Frohmann, Peder Bagge Hansen, Peter Lehner, Andre Fonseca Prince, Ryo Sakagami, Bernhard Vodermayer, Armin Wedler, Anko Börner, Heinz-Wilhelm Hübers   +11 more
doaj   +1 more source

An Interpretable Machine Vision Approach to Human Activity Recognition using Photoplethysmograph Sensor Data [PDF]

, 2018
The current gold standard for human activity recognition (HAR) is based on the use of cameras. However, the poor scalability of camera systems renders them impractical in pursuit of the goal of wider adoption of HAR in mobile computing contexts ...
Brophy, Eoin, Smeaton, Alan F., Veiga, José Juan Dominguez, Wang, Zhengwei, Ward, Tomas E.   +4 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source