Results 91 to 100 of about 722,415 (286)
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
IEEE Access, 2019 Modulation format identification is an important part of optical performance monitoring in elastic optical networks. We propose a modulation format identification scheme based on the information entropy analysis of received optical communication signal ...
Zhao Zhao, Aiying Yang, Peng Guo
doaj +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
IEEE Photonics Journal, 2018 In this paper, a novel optical comparison operation for phase-shift keying (PSK) modulated signal has been proposed by using optical delayed interferometer to realize an advanced functional component for future optical network.
Yohei AIKAWA
doaj +1 more source
Image Reconstruction in Optical Interferometry
, 2009 This tutorial paper describes the problem of image reconstruction from interferometric data with a particular focus on the specific problems encountered at optical (visible/IR) wavelengths.
Giovannelli, Jean-François +1 more
core +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Improved Optical Signal Processing with On-Chip Programmable Filter
PhotonicsBandwidth-limited transmitters have become a severe issue with the rapid growth of bandwidth-hungry services. We investigate the impact of an on-chip optical pre-emphasizer on a bandwidth-limited transmitter and quantitatively analyze the results of ...
Tiantian Li +8 more
doaj +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
A broadband RF continuously variable time delay device [PDF]
A method for implementation of continuously variable time delay of broadband RF signals is described. The method uses Bragg Cell and optical heterodyne technology.
Freyre, F. W.
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source