Results 101 to 110 of about 722,415 (286)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Towards in-fiber silicon photonics

The state of the art of silicon optical fibers fabricated via the high pressure chemical deposition technique will be reviewed. The optical transmission properties of step index silicon optical fibers will be presented, including investigations of the ...
Badding, J.V., Day, T.D., Healy, N., Mehta, P., Peacock, A.C., Sazio, P.J.A., Shen, L.   +6 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Integration of Brillouin and passive circuits for enhanced radio-frequency photonic filtering

APL Photonics, 2019
Signal processing using on-chip nonlinear or linear optical effects has shown tremendous potential for RF photonic applications. Combining nonlinear and linear elements on the same photonic chip can further enable advanced functionality and enhanced ...
Yang Liu, Amol Choudhary, Guanghui Ren, Khu Vu, Blair Morrison, Alvaro Casas-Bedoya, Thach G. Nguyen, Duk-Yong Choi, Pan Ma, Arnan Mitchell, Stephen J. Madden, David Marpaung, Benjamin J. Eggleton   +12 more
doaj   +1 more source

Application of laser anemometry in turbine engine research [PDF]

The application of laser anemometry to the study of flow fields in turbine engine components is reviewed. Included are discussions of optical configurations, seeding requirements, electronic signal processing, and data processing.
Seasholtz, R. G.
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Towards large-scale programmable silicon photonic chip for signal processing

Nanophotonics
Optical signal processing has been playing a crucial part as powerful engine for various information systems in the practical applications. In particular, achieving large-scale programmable chips for signal processing are highly desirable for high ...
Xie Yiwei, Wu Jiachen, Hong Shihan, Wang Cong, Liu Shujun, Li Huan, Ju Xinyan, Ke Xiyuan, Liu Dajian, Dai Daoxin   +9 more
doaj   +1 more source