Results 111 to 120 of about 723,186 (293)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Multi-wavelength optical information processing with deep reinforcement learning

Light: Science & Applications
Multi-wavelength optical information processing systems are commonly utilized in optical neural networks and broadband signal processing. However, their effectiveness is often compromised by frequency-selective responses caused by fabrication ...
Qiuquan Yan, Hao Ouyang, Zilong Tao, Meili Shen, Shiyin Du, Jun Zhang, Hengzhu Liu, Hao Hao, Tian Jiang   +8 more
doaj   +1 more source

An analysis of signal processing algorithm performance for cortical intrinsic optical signal imaging and strategies for algorithm selection [PDF]

, 2017
Jordan Alexander Turley, Karolina Zalewska, Michael Nilsson, Frederick R. Walker, Sarah J. Johnson   +4 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Multifunctional mixed analog/digital signal processor based on integrated photonics

Opto-Electronic Science
Photonic signal processing offers a versatile and promising toolkit for contemporary scenarios ranging from digital optical communication to analog microwave operation.
Yichen Wu, Qipeng Yang, Bitao Shen, Yuansheng Tao, Xuguang Zhang, Zihan Tao, Luwen Xing, Zhangfeng Ge, Tiantian Li, Bowen Bai, Haowen Shu, Xingjun Wang   +11 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Complementary-View SAR Target Recognition Based on One-Shot Learning

Remote Sensing
The consistent speckle noise in SAR images easily interferes with the semantic information of the target. Additionally, the limited quantity of supervisory information available in one-shot learning leads to poor performance.
Benteng Chen, Zhengkang Zhou, Chunyu Liu, Jia Zheng   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

All-optical signal processing in photonic structures with shifting bands [PDF]

, 2004
E. Ya. Glushko
openalex   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source