Results 71 to 80 of about 723,186 (293)

Nonlinear Optical Signal Processing for Tbit/s Ethernet Applications

International Journal of Optics, 2012
We review recent experimental demonstrations of Tbaud optical signal processing. In particular, we describe a successful 1.28 Tbit/s serial data generation based on single polarization 1.28 Tbaud symbol rate pulses with binary data modulation (OOK) and ...
L. K. Oxenløwe, M. Galili, H. C. Hansen Mulvad, H. Hu, J. L. Areal, E. Palushani, H. Ji, A. T. Clausen, P. Jeppesen   +8 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Real-Time Optical Spectrum Fourier Transform With Time–Bandwidth Product Compression

IEEE Photonics Journal, 2018
We propose and experimentally demonstrate a photonic technique for Fourier transformation of broadband optical spectrum and compression of time–bandwidth product (TBP) simultaneously.
Hao Sun, Xinyi Zhu, Wei Li, Ninghua Zhu, Ming Li   +4 more
doaj   +1 more source

Non-Integer-Oversampling Digital Signal Processing for Coherent Passive Optical Networks [PDF]

, 2023
Haide Wang, Ji Zhou, Jinyang Yang, Jianrui Zeng, Weiping Liu, Changyuan Yu, Fan Li, Zhaohui Li   +7 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Laser Remote Sensing of Seismic Wave with Sub-Millimeter Scale Amplitude Based on Doppler Characteristics Extracted from Wavefront Sensor

Photonics
Laser remote sensing of earthquake waves has the potential to be used in many applications. This article shows a Doppler model for laser remote sensing of seismic waves based on a wavefront sensor. The longitudinal vibration wave is analyzed using remote
Quan Luo, Hongsheng Luo, Guihan Wu, Xiang Ji, Jinshan Su, Wei Jiang   +5 more
doaj   +1 more source

Energy Consumption and Energy Density in Optical and Electronic Signal Processing

IEEE Photonics Journal, 2011
We compare the energy consumption of digital optical and digital electronic signal processing circuits, including the contributions to energy consumption of the optical to electrical (O/E) converters and electrical to optical (E/O) converters, and the ...
Rodney S. Tucker, Kerry Hinton
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Picosecond optical pulse processing using a terahertz-bandwidth reconfigurable photonic integrated circuit

Nanophotonics, 2018
Chip-scale integrated optical signal processors promise to support a multitude of signal processing functions with bandwidths beyond the limit of microelectronics.
Xie Yiwei, Zhuang Leimeng, Lowery Arthur J.   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source