Results 31 to 40 of about 76,081 (234)

Silicon Non-Blocking 4 × 4 Optical Switch Chip Integrated With Both Thermal and Electro-Optic Tuners

IEEE Photonics Journal, 2019
We experimentally demonstrate an integrated strictly non-blocking silicon 4 × 4 optical switch chip that can be operated in both thermo-optic (TO) and electro-optic (EO) switching modes.
Liangjun Lu, Xiaorui Li, Wei Gao, Xin Li, Linjie Zhou, Jianping Chen   +5 more
doaj   +1 more source

On-chip silicon photonic controllable 2 × 2 four-mode waveguide switch

Scientific Reports, 2021
Multimode optical switch is a key component of mode division multiplexing in modern high-speed optical signal processing. In this paper, we introduce for the first time a novel 2 × 2 multimode switch design and demonstrate in the proof-of-concept.
Cao Dung Truong, Duy Nguyen Thi Hang, Hengky Chandrahalim, Minh Tuan Trinh   +3 more
doaj   +1 more source

Optical burst switching with large switching overhead [PDF]

2006 IEEE International Conference on Communications, 2006
The optical burst switching (OBS) schemes to date assume that the switching overhead at intermediate nodes is either negligible or can be considered as part of the processing delay of the control packet. In this paper, we will show that the switching overhead can have a significant impact on the performance of OBS.
Li, VOK, Wai, PKA, Li, G, Li, CY
openaire   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

LIQUID CRYSTAL BASED OPTICAL SWITCHES [PDF]

Molecular Crystals and Liquid Crystals, 2004
Optical switches using two electro-optical effects in liquid crystals are proposed and investigated for incorporation in a switch matrix for optical networks. These two devices employ selective reflection in cholesteric layers and total reflection at the border between glass and nematic liquid crystal.
Semenova, Yuliya, Dovgalets, S., Panarin, Yuri, Farrell, Gerald   +3 more
openaire   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Hybrid Switch of Correlation and Squeezing Using Resonant and Off-Resonant Excitation Spectrum in Nitrogen-Vacancy Center Diamond

IEEE Photonics Journal, 2019
Optical hybrid communication is one of the key fields of quantum communications, where scientists are focusing to integrate classical and quantum system as single hybrid system.
Faizan Raza, Al Imran, Abubakkar Khan, Habib Ullah, Siqiang Zhang, Siqi Xiong, Irfan Ahmed, Yanpeng Zhang   +7 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source