Results 71 to 80 of about 380,624 (313)
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Design of Optical Tunnel Switching Networks for Big Data Applications
In this paper, we proposed large-scale optical tunnel switching networks based on the Torus topology network with WSS (Wavelength Selective Switch) for future big data applications.
Yuh-Jiuh Cheng +3 more
doaj +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Switching of three-dimensional optical cages using spatial coherence engineering
Precisely capturing and manipulating microparticles is the key to exploring microscopic mysteries. Optical tweezers play a crucial role in facilitating these tasks. However, existing optical tweezers are limited by their dependence on specific beam modes,
Ying Xu +6 more
doaj +1 more source
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Organization of the channel-switching process in parallel computer systems based on a matrix optical switch [PDF]
After a classification and analysis of electronic and optoelectronic switching devices, the design principles and structure of a matrix optical switch is described.
Golomidov, Y. V. +3 more
core +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Performance-Improved Broadcast-and-Select Optical Switch Module Based on EAM-Gate Array
Performance improvement of a broadcast-and-select (B&S) optical switch based on an electro-absorption modulator (EAM)-gate array is presented.
Y. Muranaka +4 more
doaj +1 more source
Equivalent random analysis of a buffered optical switch with general interarrival times [PDF]
We propose an approximate analytic model of an optical switch with fibre delay lines and wavelength converters by employing Equivalent Random Theory. General arrival traffic is modelled by means of Gamma-distributed interarrival times.
Barry, Liam P. +2 more
core
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source

