Results 61 to 70 of about 383,407 (335)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Design and analysis of a 2D photonic crystal based parallelogram-shaped cavity with open corners for optical switching [PDF]
EPJ Web of ConferencesIn this paper, we designed a 2×2 optical switch using a two- dimensional photonic crystal (2D PC) based on interference principle. For the first time, an air-hole slab-structure-based photonic switch is proposed.
Sreevani N.R.G. +2 more
doaj +1 more source
Controlling the phase of a light beam with a single molecule
, 2011 We employ heterodyne interferometry to investigate the effect of a single organic molecule on the phase of a propagating laser beam. We report on the first phase-contrast images of individual molecules and demonstrate a single-molecule electro-optical ...
A. Renn +9 more
core +1 more source
Tunable Directional Filter for Mid-Infrared Optical Transmission Switching [PDF]
, 2022 Andrew Butler +2 more
openalex +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A microfluidic 2×2 optical switch [PDF]
, 2004 A 2×2 microfluidic-based optical switch is proposed and demonstrated. The switch is made of an optically clear silicon elastomer, Polydimethylsiloxane (PDMS), using soft lithography.
Campbell, Kyle +6 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
IEEE Photonics Journal, 2017 We propose and experimentally demonstrate an all-optical switch based on a fiber-chip-fiber opto-mechanical system driven by thermal radiation. The two optical fibers are both designed as movable cantilever structures with a free-hanging length.
Li Liu, Jin Yue, Zhihua Li
doaj +1 more source
Observation of electro-activated localized structures in broad area VCSELs [PDF]
, 2014 We demonstrate experimentally the electro-activation of a localized optical structure in a coherently driven broad-area vertical-cavity surface-emitting laser (VCSEL) operated below threshold.
Agranat, A. J. +7 more
core +3 more sources
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source