Results 41 to 50 of about 2,211,122 (242)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Microscopic Control and Detection of Ultracold Strontium in Optical-Tweezer Arrays
Physical Review X, 2018 Optical tweezers provide a versatile platform for the manipulation and detection of single atoms. Here, we use optical tweezers to demonstrate a set of tools for the microscopic control of atomic strontium, which has two valence electrons.
M. A. Norcia +2 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.Despite benefits to storage stability and handleability of aluminum scrap, octadecyl phosphonic acid (ODPA) SAMs reduce the tensile strength of wires produced using friction‐induced recycling. Etching and methyl diphosphonic acid (MDPA) coatings, however, have little effect.
Timothy D. Goller +3 more
wiley +1 more source
Optical tweezing of microparticles and cells using silicon-photonics-based optical phased arrays
Nature CommunicationsIntegrated optical tweezers have the potential to enable highly-compact, low-cost, mass-manufactured, and broadly-accessible optical manipulation when compared to standard bulk-optical tweezers.
Tal Sneh +5 more
doaj +1 more source
Drug Targeting Model of Composite Gold-Tourmaline for Cells Enhancing Applications
Nano Biomedicine and Engineering, 2015 The drug delivery and targeting method of gold tourmaline composite atoms generated by optical tweezers in a micro-optical device system is proposed.
Preecha P. Yupapin, Senee Suwandee
doaj +1 more source
Optical Detection of Cellular Signals at Material Interfaces
Advanced Healthcare Materials, EarlyView.Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
Advanced Materials, EarlyView.Azobenzene photoswitches translate molecular‐scale E/Z photoisomerization into macroscopic material responses and device‐level photonic functions. This Review highlights how azobenzene research has evolved from molecular photochemistry to photoalignment, mass migration, photomechanics, and heat release, ultimately enabling holography, reconfigurable ...
Heeju Son +20 more
wiley +1 more source
Optical micromanipulation using ultrashort pulsed laser sources [PDF]
, 2007 In this thesis two previously separate fields of study are brought together: optical micromanipulation and ultrashort laser research. Here, the benefits of combining the high peak powers of ultrashort pulsed lasers and conventional optical ...
Little, Helen
core +2 more sources
Magnetic tweezers to capture the fast-folding λ6-85 in slow motion
Communications PhysicsForce spectroscopy gives access to the underlying free energy landscape of protein folding. Proteins exhibit folding rates between microseconds and hours.
César Augusto Quintana-Cataño +5 more
doaj +1 more source