Results 61 to 70 of about 2,534,041 (331)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Microscopic Control and Detection of Ultracold Strontium in Optical-Tweezer Arrays

open access: yesPhysical Review X, 2018
Optical tweezers provide a versatile platform for the manipulation and detection of single atoms. Here, we use optical tweezers to demonstrate a set of tools for the microscopic control of atomic strontium, which has two valence electrons.
M. A. Norcia   +2 more
doaj   +1 more source

Microfabrication by optical tweezers [PDF]

open access: yesSPIE Proceedings, 2011
A new method to fabricate microstructures built by polymer microparticles using a bottom-up technique is presented. The microstructures find broad application in micro-fluidics technology, photonics and tissue-engineering. The handling of the particles is realized by a holographic optical tweezers setup, ensuring the precise allocation of the particles
Cemal Esen   +3 more
openaire   +2 more sources

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

open access: yesAdvanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari   +11 more
wiley   +1 more source

Stable, Easy‐to‐Handle, Fully Autologous Electrospun Polymer‐Peptide Skin Equivalent for Severe Burn Injuries

open access: yesAdvanced Functional Materials, EarlyView.
A bioengineered skin equivalent composed of electrospun poly(ε‐caprolactone) (PCL) and the bioactive peptide Fmoc‐FRGD is developed for severe burn treatment. This scaffold promotes full‐thickness skin regeneration by supporting cellular adhesion and integration. In‐vitro and in‐vivo studies show enhanced mechanical stability, accelerated wound closure,
Dana Cohen‐Gerassi   +11 more
wiley   +1 more source

Optical tweezing of microparticles and cells using silicon-photonics-based optical phased arrays

open access: yesNature Communications
Integrated optical tweezers have the potential to enable highly-compact, low-cost, mass-manufactured, and broadly-accessible optical manipulation when compared to standard bulk-optical tweezers.
Tal Sneh   +5 more
doaj   +1 more source

Drug Targeting Model of Composite Gold-Tourmaline for Cells Enhancing Applications

open access: yesNano Biomedicine and Engineering, 2015
The drug delivery and targeting method of gold tourmaline composite atoms generated by optical tweezers in a micro-optical device system is proposed.
Preecha P. Yupapin, Senee Suwandee
doaj   +1 more source

Plasmonic optical tweezers based on nanostructures: fundamentals, advances and prospects [PDF]

open access: yesNanophotonics, 2019
The ability of metallic nanostructures to confine light at the sub-wavelength scale enables new perspectives and opportunities in the field of nanotechnology.
D. Kotsifaki, S. N. Chormaic
semanticscholar   +1 more source

Optical tweezers for drug discovery

open access: yesDrug Discovery Today, 2023
The time taken and the cost of producing novel therapeutic drugs presents a significant burden - a typical target-based drug discovery process involves computational screening of drug libraries, compound assays and expensive clinical trials. This review summarises the value of dynamic conformational information obtained by optical tweezers and how this
Matthew T J, Halma   +2 more
openaire   +2 more sources

Versatile Green Transfer of Magnetoelectronics with Loss‐Free Performance and High Adhesion for Interactive Electronics

open access: yesAdvanced Functional Materials, EarlyView.
An environmentally friendly transfer printing method of nm‐thick giant magnetoresistive (GMR) sensors is demonstrated. This method, relying on water and biocompatible polyvinyl alcohol (PVA) polymer without the need of complex treatments, allows transferring thin films to a wide range of biological, organic, and inorganic substrates.
Olha Bezsmertna   +7 more
wiley   +1 more source

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