Results 101 to 110 of about 4,779 (300)

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

open access: yesAdvanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang   +10 more
wiley   +1 more source

Effect of Alkyl Chain Length on the Bandgap, Ferroelectric, and Photoelectric Properties of Lead‐Based Molecular Ferroelectrics

open access: yesAdvanced Science, EarlyView.
This study develops a novel 2D molecular ferroelectric [C6N2H18]PbI4 with polarization enhanced photovoltaics. It systematically investigates the effect of alkylamine spacer cation chain lengths on the band gap, ferroelectric, and photoelectric properties, offering new design strategies.
Ganghua Zhang   +7 more
wiley   +1 more source

Dosimetry for low-energy electron beam applications at Fraunhofer FEP

open access: yesNukleonika
Accelerating electrons to achieve chemical and biological effects is a well-established competence of Fraunhofer FEP. Today, there is a large variety of low-energy electron beam applications with a broad range of absorbed doses, e.g.
Teichmann Tobias   +9 more
doaj   +1 more source

Sedimentology and chronology of unconsolidated alluvial fans of the Quadrilátero Ferrífero (Central Brazil): implications for landscape dynamics in the Late Quaternary

open access: yesRevista Brasileira de Geomorfologia
This paper identifies and discusses the paleoenvironmental characteristics of the Quadrilátero Ferrífero based on studies of unconsolidated alluvial fans and the chronological organization of their respective sedimentary facies. These alluvial fans were
Fabrício Antonio Lopes   +3 more
doaj   +1 more source

Dating the megalithic culture of laos: Radiocarbon, optically stimulated luminescence and U/Pb zircon results. [PDF]

open access: yesPLoS One, 2021
Shewan L   +11 more
europepmc   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu   +13 more
wiley   +1 more source

Nanostructured carbon-doped α-Al2O3 microspheres: Scalable synthesis and luminescence properties

open access: yesNext Materials
This study presents a novel method of synthesizing alumina doped with carbon through the scalable spray drying process. In the first step nanostructured Al(OH)3 microspheres are synthesized by spray drying with excellent flowability, narrow size ...
Pankaj Singh   +6 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

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