Results 71 to 80 of about 463,519 (308)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The MAORY first-light adaptive optics module for E-ELT

open access: yes, 2015
The MAORY adaptive optics module is part of the first light instrumentation suite for the E-ELT. The MAORY project phase B is going to start soon.
Ragazzoni R.   +79 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Анализ характеристик устройств регистрации волновых возмущений в среде с использованием оптических, СВЧ и ультразвуковых лучей

open access: yesНаучный вестник МГТУ ГА, 2016
Рассматриваются характеристики устройств регистрации акустических волн в воздухе и воде с использованием оптических, СВЧ и ультразвуковых лучей. Приводятся результаты исследования акустической чувствительности, направленных свойств и ширины полосы ...
V. D. Roubtsov, S. A. Dubyanskiy
doaj  

Outlier Ensemble Based on Isolation Forest: The CBOEA Approach

open access: yesFoundations of Computing and Decision Sciences
Outliers are instances that deviate from the norm. In certain fields, their detection is crucial since they are often indicators of interesting events such as system faults and deliberate human actions.
Chaabouni Ali, Boujelben Mohamed Ayman
doaj   +1 more source

An experimental Rayleigh laser guide star ground layer adaptive optics system for the William Herschel telescope [PDF]

open access: yes, 2005
The design of an experimental ground layer adaptive optics (GLAO) system that uses a low altitude Rayleigh laser guide star as a wavefront reference source is presented.
Morris, T J, Morris, T. J.
core  

Manifold optics

open access: yesOptics Letters
Transformation optics establishes an equivalence relationship between gradient media and curved space, unveiling intrinsic geometric properties of gradient media. However, this approach based on curved spaces is concentrated on two-dimensional manifolds, namely, curved surfaces.
Hongming Shen   +3 more
openaire   +3 more sources

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Complementary Metal Oxide Semiconductor-Based Optical Detection System for Fluidic Cellular Medium pH Quantification

open access: yesPhotonics
Accurate pH sensing is essential for the effective physiological control of the culture media in organ-on-a-chip (OoC) systems. This work proposes a miniaturized optical detection system, based on optical transmittance, for pH level quantification of the
André A. Santos   +5 more
doaj   +1 more source

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