Results 91 to 100 of about 521,864 (308)
Self-imaging and caustics in two-dimensional surface plasmon optics [PDF]
, 2008 We study theoretically the surface plasmon electromagnetic field in the plane of the interface along which it propagates. Arbitrary Surface plasmon fields are expressed by a linear superposition of elementary surface plasmon modes, thus obtaining an ...
GABRIEL CONSTANTINO MARTINEZ NICONOFF +2 more
core
High numerical aperture hybrid optics for two-photon polymerization
, 2022 S.7994-8005We report on an immersion hybrid optics specially designed for focusing ultrashort laser pulses into a polymer for direct laser writing via two-photon polymerization.
Burmeister, Frank +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Hybrid optics for focusing ultrashort laser pulses
, 2022 S.1516-1518We present a specially designed hybrid optics comprising refraction and diffraction effects for tight spatial and temporal focusing of ultrashort laser pulses.
Fuchs, U., Tünnermann, A., Zeitner, U.
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Bottom–Up Metasurfaces for Biotechnological Applications
Advanced ScienceMetasurfaces are the 2D counterparts of metamaterials, and their development is accelerating rapidly in the past years. This progress enables the creation of devices capable of uniquely manipulating light, with applications ranging from optical ...
Francesca Petronella +4 more
doaj +1 more source
Modulation-assisted tunneling in laser-fabricated photonic Wannier–Stark ladders
New Journal of Physics, 2015 We observe Wannier–Stark (W–S) localization in curved photonic lattices, realized using arrays of evanescently coupled optical waveguides. By correctly tuning the strength of inter-site coupling in the lattice, we observe that W–S states become ...
Sebabrata Mukherjee +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source