Results 91 to 100 of about 942,030 (275)
, 2016 The advent of Wide Field Adaptive Optics (WFAO) systems marks the beginning of a new era in high spatial resolution imaging. The newly commissioned Gemini South Multi-Conjugate Adaptive Optics System (GeMS) combined with the infrared camera Gemini South ...
Andersen, M. +8 more
core +3 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
How to Automate a Kinematic Mount Using a 3D Printed Arduino-Based System
Inventions, 2018 We demonstrate a simple, flexible and cost-effective system to automatize most of the kinematic mounts available nowadays on the market. It combines 3D-printed components, an Arduino board, stepper motors and simple electronics.
Luis José Salazar-Serrano +2 more
doaj +1 more source
, 2014 We describe the design and first-light early science performance of the Shane Adaptive optics infraRed Camera-Spectrograph (ShARCS) on Lick Observatory's 3-m Shane telescope. Designed to work with the new ShaneAO adaptive optics system, ShARCS is capable
Alcott, Barry +18 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Bosonic CNOT gates with Quantum Interrogation
, 2008 We put forward a new CNOT gate scheme with atoms and ions based on quantum interrogation and a bosonic particle extension of the models of linear optics quantum computation.
Alexander Lvovsky +2 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Comparison of Regularization Methods in Fluorescence Molecular Tomography
Photonics, 2014 In vivo fluorescence molecular tomography (FMT) has been a popular functional imaging modality in research labs in the past two decades. One of the major difficulties of FMT lies in the ill-posed and ill-conditioned nature of the inverse problem in ...
Dianwen Zhu +4 more
doaj +1 more source
, 2017 We report on small student (high school) project of the Czech Academy of Sciences dealing with animal (fish) eyes and possible application in science and technology. Albeit most fishes have refractive eyes, the recent discoveries confirm that some fishes
Hudec R., Michalova S.
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source