Results 91 to 100 of about 463,519 (308)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Roadmap on transformation optics [PDF]

, 2018
Transformation Optics asks Maxwell’s equations what kind of electromagnetic medium recreate some smooth deformation of space. The guiding principle is Einstein’s principle of covariance: that any physical theory must take the same form in any ...
John B Pendry, Horsley, SAR, Philippe Tassin, Horsley, Simon, Martini, Enrica, Smolyaninova, Vera N., Ginis, Vincent, Andrew M Weiner, Quevedo-Teruel, O, Minatti, Gabriele, Paul Kinsler, Galdi, Vincenzo, Quevedo-Teruel, Oscar, Thompson, Robert T., Smolyaninova, Vera N.,, Pendry, John, Hao, Yang, Gratus, J, Martin McCall, McCall, M, Ebrahimpouri, Mahsa, Smolyaninova, Vera, Ulf Leonhardt, Hao, Yang,, Cummer, SA, Igor I Smolyaninov, Muamer Kadic, Leonhardt, U, Kadic, Muamer, Yang Hao, Mitchell-Thomas, Rhiannon, Li, Jensen,, Lai, Y, Vincenzo Galdi, Hao, Y, McCall, Martin,, Gratus, Jonathan, Minatti, G, Rhiannon C Mitchell-Thomas, Pendry, JB, Kinsler, Paul,, Robert T Thompson, Mahsa Ebrahimpouri, Zhu, Jian, Lukens, JM, Ginis, V, Smolyaninov, II, Oscar Quevedo-Teruel, Ginis, Vincent,, Pendry, John B., Zhu, Jain, Martini, E, Maci, S, Kinsler, Paul, Smolyaninov, Igor I, Stefano Maci, Lai, Yun, Horsley, S. A. R., Li, Jensen, Mitchell-Thomas, Rhiannon C., Steven A Cummer, Tassin, Philippe,, Maci, Stefano, Cummer, Steven, Lukens, Joseph M, Martin Wegener, Lukens, Joseph, Cummer, Steven A.,, Weiner, Andrew M.,, Thompson, Robert T.,, Zhu, J, McCall, Martin, Wegener, Martin,, Cummer, Steven A., Pendry, John B.,, Gratus, Jonathan,, Enrica Martini, S A R Horsley, Lukens, Joseph M.,, Joseph M Lukens, Manatti, Gabriele, Jonathan Gratus, Tassin, Philippe, Jensen Li, Leonhardt, Ulf,, Horsely, Simon, Smolyaninova, VN, Lai, Yun,, Leonhardt, Ulf, Lukens, Joseph M., Jian Zhu, Weiner, Andrew M., Li, J, Weiner, Andrew, Yun Lai, Mitchell-Thomas, RC, Smolyaninov, Igor I.,, Vincent Ginis, Horsley, S. A. R.,, Galdi, Vincenzo,, Weiner, AM, Weiner, Andrew M, Wegener, Martin, Vera N Smolyaninova, Horsley, S. A.R., Mitchell-Thomas, Rhiannon C.,, Minatti, Gabriele,, Zhu, Jian,, Ebrahimpouri, M, Kadic, M, Smolyaninov, Igor I., Tassin, P, Thompson, RT, Gabriele Minatti, Ebrahimpouri, Mahsa,, Martini, Enrica,, Galdi, V, Quevedo-Teruel, Oscar,, Thompson, Robert, Pendy, John, Kinsler, P, Wegener, M, Smolyaninov, Igor, Maci, Stefano,, Kadic, Muamer,   +124 more
core   +1 more source

Introduction to Visual and Physiological Optics feature issue of Biomedical Optics Express and JOSA A

, 2023
This feature issue collects articles presented at the tenth Visual and Physiological Optics meeting (VPO2022), held August 29–31, 2022, in Cambridge, UK.
Schwarz, Christina,, Vohnsen, Brian,, Lundström, Linda,, Tabernero, Juan,   +3 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Focus issue introduction: Nonlinear optics 2013

, 2013
Nonlinear Optics has continued to develop over the last few years at an extremely fast pace, with significant advances being reported in nonlinear optical metamaterials, optical signal processing, quantum optics, nonlinear optics at subwavelength scale ...
Dadap, J. I.,, Panoiu, N. C.,, Karlsson, Magnus, Dadap, J. I., Panoiu, N. C., Karlsson, Magnus,   +5 more
core   +1 more source

Broadband Thermal Imaging using Meta-Optics

, 2023
Subwavelength diffractive optics known as meta-optics have demonstrated the potential to significantly miniaturize imaging systems. However, despite impressive demonstrations, most meta-optical imaging systems suffer from strong chromatic aberrations ...
Anna Wirth-Singh (14366190), Orrin Kigner (10893084), Zheyi Han (137514), Joshua R. Hendrickson (4810263), Vishwanath Saragadam (14356164), Phillip W. C. Hon (16648674), Zachary Coppens (15400394), Saswata Mukherjee (14360079), Quentin A. A. Tanguy (14360076), Joshua Rollag (16648671), Ashok Veeraraghavan (3188601), Ricky Gibson (4810254), Arka Majumdar (1400788), Luocheng Huang (13818297), Johannes E. Fröch (14365734), Karl F. Böhringer (14365737)   +15 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Controlling optical-cavity locking using reinforcement learning

Machine Learning: Science and Technology
This study applies an effective methodology based on Reinforcement Learning to a control system. Using the Pound–Drever–Hall locking scheme, we match the wavelength of a controlled laser to the length of a Fabry-Pérot cavity such that the cavity length ...
Edoardo Fazzari, Hudson A Loughlin, Chris Stoughton   +2 more
doaj   +1 more source

Matching optics for Gaussian beams

, 1991
A system of matching optics for Gaussian beams is described. The matching optics system is positioned between a light beam emitter (such as a laser) and the input optics of a second optics system whereby the output from the light beam emitter is ...
Gunter, William D.
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source