Results 121 to 130 of about 268,057 (260)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Modifications of the Optimal Auxiliary Function Method to Fractional Order Fornberg-Whitham Equations

Computer Modeling in Engineering & Sciences, 2023
Hakeem Ullah, Mehreen Fiza, Ilyas Khan, Abd Allah A. Mosa, Saeed Islam, Abdullah Mohammed   +5 more
openaire   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

On the “Tantawy technique” and other methods for analyzing fractional Fokker–Plank type equations

Journal of Low Frequency Noise, Vibration and Active Control
The family of Fokker–Planck (FP) equations has been widely used in various physical applications, especially optical physics. It has proven effective in understanding numerous nonlinear phenomena observed in optical fiber.
Aljawhara H Almuqrin, CGL Tiofack, DV Douanla, A Mohamadou, Weaam Alhejaili, Sherif ME Ismaeel, Samir A El-Tantawy   +6 more
doaj   +1 more source

A novel approach to solving nonlinear fractional wave-like differential equations

Arab Journal of Basic and Applied Sciences
The optimal auxiliary function method (OAFM) is applied in this research paper to find analytical solutions to fractional-order strongly nonlinear wave-like differential equations with variable coefficients.
Ibrahim Mahariq, Muhammad Nawaz, Mehreen Fiza, Hakeem Ullah, Ali Akgül, Allanazar Qutlimurotov, Seham M Al-Mekhlafi   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

An efficient model‐free adaptive optimal control of continuous‐time nonlinear non‐zero‐sum games based on integral reinforcement learning with exploration

IET Control Theory & Applications
To reduce the learning time and space occupation, this study presents a novel model‐free algorithm for obtaining the Nash equilibrium solution of continuous‐time nonlinear non‐zero‐sum games.
Lei Guo, Wenbo Xiong, Yuan Song, Dongming Gan   +3 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source