Results 121 to 130 of about 12,436,371 (298)
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Optimal Control and Biomechanics of Ambulation with Spring-Loaded Crunches
International Journal of Advanced Robotic Systems, 2011 Standard underarm or forearm crutches have some drawbacks induced by their rigid legs. Sping‐ loaded crutches can reduce the impact effect. However, whether or not they also improve propulsion is an open problem.
Guangyu Liu +3 more
doaj
A Boundary Optimal Control Identification Problem
, 2020 Optimal control methods are applied in various problems and can be efficient also for solving inverse problems, such as parameter identification and boundary control which arise in many important applications. For boundary optimal control methods one can identify conditions on an inaccessible part of the boundary by letting them play the role of a ...
Axelsson, Owe +2 more
openaire +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Exact penalty functions for optimal control problems [PDF]
openA novel technique to solve optimal control problems with state constraints is proposed. We exploit the theory of exact penalty functions, used in mathematical programming, to construct a systematic procedure to transform two classes of problems with ...
GRIMALDI, RICCARDO ALESSANDRO
core
A Stable Self-Learning Optimal Fuzzy Control System
, 2011 The issue of developing a stable self-learning optimal fuzzy control system is discussed in this paper. Three chief objectives are accomplished: 1) To develop a self-learning fuzzy controller based on genetic algorithms.
Lin, Sinn-cheng; Chen, Yung-yaw
core +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Optimal and sub-optimal control in Dengue epidemics
, 2001 This work concerns the application of the optimal control theory to Dengue epidemics. The dynamics of this insect-borne disease is modelled as a set of non-linear ordinary differential equations including the effect of educational campaigns organized to ...
Yoneyama, T., Caetano, MAL
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source