Results 51 to 60 of about 5,822,632 (252)

A New Efficient Method to Solve Bi-Objective Transportation Problems Under Fuzzy Parameters

مجلة بغداد للعلوم
The transportation problem (TP) is a classical optimization problem in operations research and logistics. Due to several factors, real-life situations may have inconsistent supply, demand, and unit transportation costs.
Ramakant Sharma, Sohan Lal Tyagi
doaj   +1 more source

The Missouri compromise revisited [PDF]

, 1990
This study concentrates on the period from the introduction of the Tallmadge amendment in February 1819 to the settling of the controversy with the famous Compromise in March 1820.
Robinson, David Paul
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Valuing Compromise for the Common Good [PDF]

, 2013
Pursuing the common good in a pluralist democracy is not possible without making compromises. Yet the spirit of compromise is in short supply in contemporary American politics.
Thompson, Dennis, Gutmann, Amy
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A robust intuitionistic fuzzy framework for optimizing emergency response strategies under uncertain disaster risk conditions

Ain Shams Engineering Journal
Amid rising global disasters, the development of effective emergency response strategies (ERS) under uncertainty remains a major challenge. To address the imprecision of expert ratings, this paper proposes a hybrid multi-criteria decision-making model ...
Shi Yin, Muhammad Safdar Nazeer, Munazza Amin, Kifayat Ullah, Zeeshan Ali, Yilun Shang, Nan Zhang   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

On the equivalence between compromise programming and the use of composite compromise metrics. [PDF]

This paper analyzes the relationship between Compromise Programming and a close relative called Composite Programming that is based on the use of composite metrics.
Carlos Romero, Francisco J. André
core  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

A study on the optimal allocation of photovoltaic storage capacity for rural new energy microgrids based on double-layer multi-objective collaborative decision-making

Sustainable Energy Research
Aiming at the problems of low energy efficiency and unstable operation in the optimal allocation of optical storage capacity in rural new energy microgrids, this paper proposes an optimization method based on two-layer multi-objective collaborative ...
Huixuan Li, Peng Li, Xianyu Yue, Yongle Zheng, Wenjing Zu, Hongkai Zhang   +5 more
doaj   +1 more source