Results 61 to 70 of about 5,822,632 (252)

Can Game Theory Help to Mitigate Water Conflicts in the Syrdarya Basin?

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2017
This paper focuses on methods to resolve the ongoing conflict between countries in the Syrdarya Basin, namely Kyrgyzstan and Uzbekistan, over water allocation. It addresses the problem by using the cooperative games framework.
Lea Melnikovová
doaj   +1 more source

Optimal Coastal Land Use and Management in Krabi, Thailand: Compromise Programming Approach [PDF]

open access: yes
This paper identifies the optimal options of Krabi’s coastal land use to facilitate the final planning decision. Through compromise programming approach, the optimization models with respect to the weights assigned to two objectives of maximizing the net
Tipparat Pongthanapanich
core  

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Multiobjective TOU Pricing Optimization Based on NSGA2

open access: yesJournal of Applied Mathematics, 2014
Fast and elitist nondominated sorting generic algorithm (NSGA2) is an improved multiobjective genetic algorithm with good convergence and robustness. The Pareto optimal solution set using NSGA2 has the character of uniform distribution. This paper builds
Huilan Jiang   +3 more
doaj   +1 more source

FUZZY LOGIC AND COMPROMISE PROGRAMMING IN PORTFOLIO MANAGEMENT [PDF]

open access: yes
The objective of this paper is to develop a portfolio optimization technique that is simple enough for an individual with little knowledge of economic theory to systematically determine his own optimized portfolio. A compromise programming approach and a
Featherstone, Allen M., Duval, Yann
core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Multi-Objective PID Controller Optimization for Quanser Aero 2 Using NSGA-II: Simulation and Hardware Implementation

open access: yesAlgerian Journal of Signals and Systems
This paper addresses the challenge of optimal Proportional-Integral-Derivative (PID) controller tuning for coupled Multi-Input Multi-Output (MIMO) mechatronic systems and validates the solution on a Quanser Aero 2 dual-rotor helicopter platform.
Ratiba FELLAG   +2 more
doaj   +1 more source

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