Results 91 to 100 of about 23,064,312 (378)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Event-Triggered Asynchronous Dissipative Control for Markov Jump Systems With Unknown Probabilities

open access: yesIEEE Access
This paper investigates the issue of the event-triggered asynchronous dissipative control for Markov jump systems with unknown probabilities and packet losses. A hidden Markov model is used to describe the asynchronous problem.
Huiying Chen   +4 more
doaj   +1 more source

Robustness Analysis of a Class of Optimal Control Systems [PDF]

open access: yesModeling, Identification and Control, 1983
This paper deals with a class of optimal control systems, where the controller. in addition to minimizing a quadratic criterion, also shall give the closed-loop system prescribed eigenvalues.
Ole A. Solheim
doaj   +1 more source

Optimal control in ink-jet printing via instantaneous control

open access: yes, 2017
This paper concerns the optimal control of a free surface flow with moving contact line, inspired by an application in ink-jet printing. Surface tension, contact angle and wall friction are taken into account by means of the generalized Navier boundary ...
Fumagalli, Ivan   +2 more
core   +1 more source

Optimal Control

open access: yes, 2004
Frequently, the engineer in charge of a process is faced with optimization problems. In fact, this may cover relatively different ideas, such as parameter identification or process optimization. It is known that the reactive feed flow rate profile for a fed-batch reactor and the temperature or pressure profile to be followed for a batch reactor, will ...
openaire   +2 more sources

Symmetries in Optimal Control

open access: yesSIAM Journal on Control and Optimization, 1987
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The Past and the Next Fifteen Years [PDF]

open access: yesModeling, Identification and Control, 1994
The scope of MIC defined by the title Modeling, Identification and Control is broad and it is impossible to do justice to all these areas in a discussion which is limited to a few pages.
Manfred Morari
doaj   +1 more source

Optimal control for rough differential equations [PDF]

open access: yes, 2006
In this note, we consider an optimal control problem associated to a differential equation driven by a H\"{o}lder continuous function g of index greater than 1/2. We split our study in two cases. If the coefficient of dg\_t does not depend on the control
Mazliak, Laurent, Nourdin, Ivan
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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