Results 111 to 120 of about 4,395,268 (339)
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Measurement + Control, 1973 In this paper, optimal and modal control theories are combined to form a new theory of optimal modal control. This theory provides a rational basis for the selection of a modal state weighting matrix which ensures that the plant matrix of the resulting ...
M. A. Woodhead, B. Porter
doaj +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Value function for regional control problems via dynamic programming and Pontryagin maximum principle [PDF]
, 2017 In this paper we focus on regional deterministic optimal control problems, i.e., problems where the dynamics and the cost functional may be different in several regions of the state space and present discontinuities at their interface.
Barles, Guy +2 more
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Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Optimal Multidimensional Droop Control for Wind Resources in DC Microgrids
Energies, 2018 The inclusion of electricity generation from wind in microgrids presents an important opportunity in modern electric power systems. Various control strategies can be pursued for wind resources connected in microgrids, and droop control is a promising ...
Kaitlyn J. Bunker, Wayne W. Weaver
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Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Optimal control for rough differential equations [PDF]
, 2006 In this note, we consider an optimal control problem associated to a differential equation driven by a H\"{o}lder continuous function g of index greater than 1/2. We split our study in two cases. If the coefficient of dg\_t does not depend on the control
Mazliak, Laurent, Nourdin, Ivan
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Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Discussion: “A Uniform Approach to the Optimum Adjustment of Control Loops” (Oldenbourg, R. C., and Sartorius, Hans, 1954, Trans. ASME, 76, pp. 1265–1273) [PDF]
, 1954 Dunstan Graham, R. C. Lathrop
openalex +1 more source