Results 121 to 130 of about 1,957,614 (317)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

An Optimal Control Approach to Sensor / Actuator Placement for Optimal Control of High Performance Buildings [PDF]

open access: yes, 2012
In this paper we consider the problem of best sensor location for optimal state estimation for real time energy efficient optimal control. Although the basic idea can be applied to the joint sensor / actuator location problem, we focus on the sensor ...
Cliff, Eugene   +3 more
core   +1 more source

Discrete Mechanics and Optimal Control for Space Trajectory Design [PDF]

open access: yes, 2011
Space trajectory design is often achieved through a combination of dynamical systems theory and optimal control. The union of trajectory design techniques utilizing invariant manifolds of the planar circular restricted three-body problem and the optimal ...
Moore, Ashley
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

New approach to stochastic optimal control and applications to economics [PDF]

open access: yes, 2005
This paper provides new insights into the solution of optimal stochastic control problems by means of a system of partial differential equations, which characterize directly the optimal control.
Rincón-Zapatero, Juan Pablo   +1 more
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Advanced Simulation-Based Methods for Optimal Stopping and Control [PDF]

open access: yes, 2018
This is an advanced guide to optimal stopping and control, focusing on advanced Monte Carlo simulation and its application to finance. Written for quantitative finance practitioners and researchers in academia, the book looks at the classical simulation ...
Schoenmakers, John G. M.   +3 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Refined H∞-Optimal Approach to Rotorcraft Flight Control [PDF]

open access: yes, 2013
[[abstract]]This paper introduces an approach to refine the H∞-optimal controller for the four-block H∞ control problem. The second singular value of the compensated system can be analyzed and synthesized with a free parameter by the proposed approach ...
Young, Jieh-Shian; Lin, Chin E.
core  

Collision-Free Multi-UAV Optimal Path Planning and Cooperative Control for Tactical Applications [PDF]

open access: yes, 2008
AIAA Guidance, Navigation and Control Conference and Exhibit 18 - 21 August 2008, Honolulu, HawaiiStemming from previous work that addressed the optimal path planning of an unmanned aerial vehicle (UAV) in obstacle-rich environments, this paper ...
Lewis, L. Ryan   +3 more
core   +1 more source

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