Results 121 to 130 of about 23,064,312 (378)
In this paper, optimal and modal control theories are combined to form a new theory of optimal modal control. This theory provides a rational basis for the selection of a modal state weighting matrix which ensures that the plant matrix of the resulting ...
M. A. Woodhead, B. Porter
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
OCTUNE: Optimal Control Tuning Using Real-Time Data with Algorithm and Experimental Results [PDF]
Mohamed Abdelkader +2 more
openalex +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Optimal Multidimensional Droop Control for Wind Resources in DC Microgrids
The inclusion of electricity generation from wind in microgrids presents an important opportunity in modern electric power systems. Various control strategies can be pursued for wind resources connected in microgrids, and droop control is a promising ...
Kaitlyn J. Bunker, Wayne W. Weaver
doaj +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Optimal control approaches for combining medicines and mosquito control in tackling dengue [PDF]
Thomas Rawson +2 more
openalex +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
An Optimal Torque Distribution Control Strategy for Four-Wheel Independent Drive Electric Vehicles Considering Energy Economy [PDF]
Jianjun Hu +4 more
openalex +1 more source

