Results 121 to 130 of about 1,879,077 (319)
Closure to “Discussions of ‘A Uniform Approach to the Optimum Adjustment of Control Loops’” (1954, Trans. ASME, 76, pp. 1273–1278) [PDF]
, 1954 Rudolf Oldenbourg, Hans Sartorius
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Molecular Oncology, EarlyView.The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita +1 more
wiley +1 more source
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Background and purpose For postoperative breast cancer patients, deformable image registration (DIR) is challenged due to the large deformations and non‐correspondence caused by tumor resection and clip insertion. To deal with it, three metrics (fiducial‐, region‐, and intensity‐based) were jointly used in DIR algorithm for improved accuracy ...
Xin Xie +6 more
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On optimal control of free boundary problems of obstacle type [PDF]
arXiv, 2018 A numerical study of an optimal control formulation for a shape optimization problem governed by an elliptic variational inequality is performed. The shape optimization problem is reformulated as a boundary control problem in a fixed domain. The discretized optimal control problem is a non-smooth and non-convex mathematical programing problem.
arxiv
Discussion: “Optimum Nonlinear Control” (Oldenburger, Rufus, 1957, Trans. ASME, 79, pp. 527–542) [PDF]
, 1957 T. M. Stout
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Molecular Oncology, EarlyView.Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric +11 more
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Statistical process control to monitor use of a web‐based autoplanning tool
Journal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022 Abstract Purpose To investigate the use of statistical process control (SPC) for quality assurance of an integrated web‐based autoplanning tool, Radiation Planning Assistant (RPA). Methods Automatically generated plans were downloaded and imported into two treatment planning systems (TPSs), RayStation and Eclipse, in which they were recalculated using ...
Hunter Mehrens +5 more
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Time Optimal Digital Computer Control of Nuclear Reactor, (III) [PDF]
, 1967 K. Monta
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Closure to “Discussions of ‘Optimum Nonlinear Control’” (1957, Trans. ASME, 79, pp. 542–545) [PDF]
, 1957 Rufus Oldenburger
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Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
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