Results 121 to 130 of about 1,651,928 (313)
Optimal investment and reinsurance with premium control
, 2019 Xin Jiang, Kam Chuen Yuen, Mi Chen
openalex +2 more sources
Optimum Load Of a Proton Exchange Membrane Fuel Cells Based on Hydrogen Flow Control
, 2023 Triyanto Pangaribowo +6 more
openalex +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
$ε$-Monotone Fourier Methods for Optimal Stochastic Control in Finance [PDF]
, 2017 Peter Forsyth, George Labahn
openalex +1 more source
Beyond just “flattening the curve”: Optimal control of epidemics with purely non-pharmaceutical interventions [PDF]
, 2020 Markus Kantner, Thomas Koprucki
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
The Optimal Open-Loop Control Construction of Complex Mechanical Plants Motion
, 2017 V.V. Bulaev, A. Yu. Goranov, V. I. Kalev
openalex +2 more sources
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source