Results 71 to 80 of about 16,385,685 (296)

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

Analyzing the MERS disease control strategy through an optimal control problem

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2018
A deterministic mathematical model of the Middle East respiratory syndrome (MERS) disease is introduced. Medical masks, supportive care treatment and a government campaign about the importance of medical masks will be involved in the model as time ...
Aldila Dipo   +4 more
doaj   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Optimal control of partially observable linear quadratic systems with asymmetric observation errors [PDF]

open access: yes, 2001
This paper deals with the optimal quadratic control problem for non-Gaussian discrete-time stochastic systems. Our main result gives explicit solutions for the optimal quadratic control problem for partially observable dynamic linear systems with ...
Romera, Rosario
core   +1 more source

Indirect Method for Optimal Control Problem Using Boubaker Polynomial

open access: yesمجلة بغداد للعلوم, 2016
In this paper, a computational method for solving optimal problem is presented, using indirect method (spectral methodtechnique) which is based on Boubaker polynomial.
Baghdad Science Journal
doaj   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah   +4 more
wiley   +1 more source

Critical Problem of Optimal Stabilization Without Control Constraints

open access: yesAxioms
This paper investigates the linear–quadratic optimal stabilization problem in the so-called critical case, that is, the situation in which the spectrum of the system matrix contains purely imaginary eigenvalues or the standard positive-definiteness ...
Volodymyr Kapustyan   +3 more
doaj   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell   +2 more
wiley   +1 more source

A fractional optimal control problem for maximizing advertising efficiency [PDF]

open access: yes
We propose an optimal control problem to model the dynamics of the communication activity of a firm with the aim of maximizing its efficiency. We assume that the advertising effort undertaken by the firm contributes to increase the firm's goodwill and ...
Andrea Ellero   +3 more
core  

Optimal control of a fractional diffusion Sturm-Liouville problem on a star graph

open access: yesAdvances in Pure and Applied Mathematics, 2022
Pasquini Soh Fotsing
doaj   +1 more source

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