Results 51 to 60 of about 17,103,137 (304)
Minimax optimal control problem with state constraints
, 2016 In this article, nondegenerate necessary conditions of optimality are derived and discussed for the so-called “minimax” optimal control problems with state constraints. In this class of problems, the data depends on an unknown parameter that takes values
Silva G. +9 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 2012 Stochastic optimization problems are the study of dynamical systems subject to random perturbations which can be controlled in order to optimize some performance criterion.
Baten, Md Azizul
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Morse Families In Optimal Control Problems [PDF]
SIAM Journal on Control and Optimization, 2015 We geometrically describe optimal control problems in terms of Morse families in the Hamiltonian framework. These geometric structures allow us to recover the classical first order necessary conditions for optimality and the starting point to run an integrability algorithm.
María Barbero-Liñán +2 more
openaire +4 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Optimal Control of the Ill-Posed Cauchy Elliptic Problem
International Journal of Differential Equations, 2015 We give a characterization of the control for ill-posed problems of oscillating solutions. More precisely, we study the control of Cauchy elliptic problems via a regularization approach which generates incomplete information.
A. Berhail, A. Omrane
doaj +1 more source
An optimal control problem for single-spot pulsed laser welding
Journal of Mathematics in Industry, 2023 We consider an optimal control problem for a single-spot pulsed laser welding problem. The distribution of thermal energy is described by a quasilinear heat equation.
Roland Herzog, Dmytro Strelnikov
doaj +1 more source
Fabrication of Silica Optical Fibers: Optimal Control Problem Solution
Fibers, 2021 In this work, a new approach to solving problems of optimal control of manufacture procedures for the production of silica optical fiber are proposed.
Vladimir Pervadchuk +4 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source