Results 31 to 40 of about 430,579 (268)

Application of the averaging method to the problems of optimal control of the impulse systems

Karpatsʹkì Matematičnì Publìkacìï, 2020
The problem of optimal control at finite time interval for a system of differential equations with impulse action at fixed moments of time as well as the corresponding averaged system of ordinary differential equations are considered. It is proved the
T.V. Koval'chuk, V.V. Mogylova, O.M. Stanzhytskyi, T.V. Shovkoplyas   +3 more
doaj   +1 more source

Time-Optimal Control Problem of Two Non-Synchronous Oscillators

Mathematics, 2022
The time-optimal control problem for a system consisting of two non-synchronous oscillators is considered. Each oscillator is controlled with a shared limited scalar control. The objective of the control is to accelerate the oscillatory system to a given
Leonid Berlin, Andrey Galyaev, Pavel Lysenko   +2 more
doaj   +1 more source

ON THE LOCAL CONTROLLABILITY FOR OPTIMAL CONTROL PROBLEMS

Matematički Vesnik
The authors consider the control system: \(\overset{.}{x}=f(x,u,t)\), \( x(t_{0})=x_{0}\), \(u(t)\in U(t)\), \(t\in \lbrack t_{0},t_{1}]\), where \(t\) is the time, \(x\in \mathbb{R}^{n}\) a state variable, \(x_{0}\) is fixed, and the control \(u(t)\in U(t)\) for a.a. \(t\in \lbrack t_{0},t_{1}]\). The set-valued mapping \(U:\mathbb{R}\rightrightarrows
Arutyunov, A. V., Zhukovskiy, S. E.
openaire   +2 more sources

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Optimal Control of Vehicle Path Tracking Problem

World Electric Vehicle Journal
In response to the problem of low optimization efficiency and low tracking accuracy in vehicle path tracking, a comprehensive optimization method is established based on the 3-DOF vehicle motion model.
Yingjie Liu, Dawei Cui
doaj   +1 more source

Fabrication of Silica Optical Fibers: Optimal Control Problem Solution

Fibers, 2021
In this work, a new approach to solving problems of optimal control of manufacture procedures for the production of silica optical fiber are proposed.
Vladimir Pervadchuk, Daria Vladimirova, Irina Gordeeva, Alex G. Kuchumov, Dmitrij Dektyarev   +4 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Optimal Control Problem for Cholera Disease and Cost-Effectiveness Analysis

Journal of Mathematical and Fundamental Sciences, 2021
Cholera is a disease that continues to be a threat to public health globally and is an indicator of inequity and lack of social development in countries. For this reason, strategies for its control need to be investigated.
Jhoana Patricia Romero-Leiton, Muhammad Ozair, Takasar Hussaing   +2 more
doaj   +1 more source