Results 41 to 50 of about 16,385,685 (296)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chebyshev Polynomials and Spectral Method for Optimal Control Problem [PDF]

open access: yesEngineering and Technology Journal, 2009
This paper presents efficient algorithms which are based on applying the idea of spectral method using the Chebyshev polynomials: including Chebyshev polynomials of the first kind, Chebyshev polynomials of the second kind and shifted Chebyshev ...
Suha Najeeb Shihab, Jabbar Abed Eleiwy
doaj   +1 more source

OPTIMAL CONTROL ON RELIABILITY PROBLEMS

open access: yesFar East Journal of Dynamical Systems, 2017
Our basic problem is that of an optimal control whose Bolza payoff is the sum between a simple integral and a function of the initial and final events whose evolution ODE is a reliability flow. The original results include: (i) a list of payoffs with reliability sense, (ii) optimal value of mean time to failure functional constrained by controlled ...
Udrişte, Constantin   +2 more
openaire   +1 more source

Adaptive optimal control of Signorini’s problem [PDF]

open access: yesComputational Optimization and Applications, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Andreas Rademacher, Korinna Rosin
openaire   +3 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Optimal Control of Vehicle Path Tracking Problem

open access: yesWorld Electric Vehicle Journal
In response to the problem of low optimization efficiency and low tracking accuracy in vehicle path tracking, a comprehensive optimization method is established based on the 3-DOF vehicle motion model.
Yingjie Liu, Dawei Cui
doaj   +1 more source

Optimal Control Problem for Cholera Disease and Cost-Effectiveness Analysis

open access: yesJournal of Mathematical and Fundamental Sciences, 2021
Cholera is a disease that continues to be a threat to public health globally and is an indicator of inequity and lack of social development in countries. For this reason, strategies for its control need to be investigated.
Jhoana Patricia Romero-Leiton   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Stochastic linear regulator problem in optimal control theory: Stochastic optimal linear regulator problem

open access: yes, 2012
Stochastic optimization problems are the study of dynamical systems subject to random perturbations which can be controlled in order to optimize some performance criterion.
Baten, Md Azizul
core   +1 more source

An Optimal Control Approach to Sensor / Actuator Placement for Optimal Control of High Performance Buildings [PDF]

open access: yes, 2012
In this paper we consider the problem of best sensor location for optimal state estimation for real time energy efficient optimal control. Although the basic idea can be applied to the joint sensor / actuator location problem, we focus on the sensor ...
Cliff, Eugene   +3 more
core   +1 more source

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